continuous-manufacturing

Two leading biotechnology companies are competing to be the first to implement cheaper, faster processes for producing drugs inside living cells, making it easier to manufacture human proteins, antibodies, and other medications.

The new approaches will be “disruptively different” says Robert Bradway, the CEO of Amgen, one of the companies pursuing a manufacturing breakthrough. Today’s systems for producing drugs in bacterial or animal cells and then isolating them are hugely expensive and can take months. With more efficient processes in place, companies could swiftly increase production of drugs in high demand, and they could produce medicines for rare diseases more cost-effectively as well.

gsk-branding

GlaxoSmithKline (GSK), the world's fourth largest drug maker, has entered into an equal joint venture agreement with Biological-E Ltd., a vaccines company based in Hyderabad, recently. The report has unveiled that the two companies are giving a shot to a six-in-one vaccine.

The companies would conduct a deep research as they are aiming at developing such a combination paediatric vaccine that protects children in developing nations like India. It is being hoped that the combination vaccine could fight not only polio, but other infectious diseases as well.

umd-academy-for-innovation

Further substantiating the school’s title as one of the most forward-thinking, cutting edge institutions the nation has to offer, the University of Maryland (UMD) has announced the launch of their first ever Academy for Innovation and Entrepreneurship today.

Due to launch in Fall 2013, the new Academy will instill a sense a culture of innovation and entrepreneurship into all areas of curriculum and colleges with the addition of classes, workshops and real world affairs that will allow students to truly grasp the meaning and need for creativity in the workplace.

health-tracking

It may just be early adopter tech types who log every step they take or calorie they burn using Fitbits, Nike Fuelbands, and other devices, but that hardly means they’re the only ones who track their health.

About 7 in 10 American adults told the Pew Internet & American Life Project that they track a health indicator like weight, diet, exercise or a symptom. But despite growing buzz around the “quantified self” movement and the explosion of gadgets and apps that help people measure and analyze everything from their activity and sleep patterns to blood glucose levels and other vital signs, just a small slice of health trackers rely on high tech devices.

bloomberg-jhu

New York Mayor Michael R. Bloomberg has pledged a $350 million gift to Johns Hopkins University to support interdisciplinary research and student financial aid, a commitment that will push his lifetime donations to his alma mater to more than $1 billion, the university announced Saturday.

Hopkins officials said they believe that Bloomberg will become the first person to reach the $1 billion level of giving to a single U.S. institution of higher education — an assertion that’s hard to verify because many donors give anonymously to universities. It is also difficult to compare the dollar value of modern donations to those in earlier eras.

gov-omalley-md

TCM is proud to announce that Governor Martin O'Malley will be the featured speaker at TCM’s Leadership Dinner.  The Governor will talk about Maryland’s knowledge economy, his legislative priorities and what’s in store for technology and biotechnology in 2013.  Our annual Leadership Dinner in Annapolis brings together the region’s technology and life sciences sectors to network and learn about important policy issues.   TCM will also share its legislative priorities for 2013.

We hope you can join us.  Last year we had over 150 executives, TCM’s Board of Directors and 50 members from the Maryland General Assembly in attendance.

nhlbi-logo-250

NHLBI Funding and Research Opportunities

The following funding opportunities from the NHLBI or other components of the National Institutes of Health, might be of interest:

NIH Guide Notices:

Please note that most links to RFAs, PAs, and Guide Notices will take you to the NIH Web site. RFPs will take you to FedBizOpps. Links to RFPs will not work past their proposal receipt date. Archived versions of RFPs posted on FedBizOpps can be found on the FedBizOpps site using the FedBizOpps search function. Under “Document to Search,” select Archived Documents.

sr-one-logo

Venture capital firm SR One has launched “OneStart,” its first business plan competition, in association with Oxbridge Biotech Roundtable and Stevenage Bioscience Catalyst. OneStart is designed to inspire and encourage its participants to become the next generation of European bio- entrepreneurs. The £100,000 winner-takes-all prize will be the largest of its kind in the world. Uniquely, OneStart will actively connect individuals from a range of institutions and backgrounds.

OneStart is open to aspiring life science entrepreneurs age 35 and younger who are studying or working in Europe. The competition will be run in stages and cover four tracks: drug discovery, medical devices, diagnostics and health information technology. The competition will team up those who have developed a technology or idea, such as academics, with individuals who have complementary backgrounds and skills, e.g. business school students, or young professionals from pharma or biotech.

NewImage

Emergent BioSolutions Inc., a pharmaceutical company, has initiated the Phase II clinical trial for NuThrax or AV7909, with the dosing of the first subject.

NuThrax, a next generation vaccine being developed as part of Emergent's anthrax franchise, consists of Anthrax Vaccine Adsorbed in combination with a novel immune stimulatory adjuvant, CPG 7909.

life-science-photo-1

A £50m venture capital fund focusing on early-stage life science and health technology companies has been launched in Scotland.

Rock Spring Ventures said it had already secured commitments worth more than £25m from a range of investors.

Backers include the universities of Glasgow, Edinburgh and Aberdeen.

jhu-whiting-engineering

Johns Hopkins University Whiting School of Engineering is collaborating with universities around the country on a project to create robots that work more efficiently with people. The National Science Foundation has funded the four-year, $3.5-million human-robot interaction research project, part of the National Robotics Initiative, a federal effort.   

“In the world of robotics, there are two natural extremes: the completely autonomous robot and the fully technically-operated robot,” says Gregory Hager, chair of the computer science department at the engineering school.

Acceleprise-Photo-1

District-based Acceleprise, a business accelerator program for companies that sell technology or services to other companies or organizations, is expanding in an effort to serve more start-ups and raise its national profile.

Started last spring, the program is the brainchild of managing partner Sean Glass and partners Allen Gannett and Collin Gutman. In addition to a $30,000 investment, participating start-ups spend several months honing business models and products at the Acceleprise office.

Quadruple-Helix

In 1953, Cambridge researchers Watson and Crick published a paper describing the interweaving ‘double helix’ DNA structure – the chemical code for all life.

Now, in the year of that scientific landmark’s 60th Anniversary, Cambridge researchers have published a paper proving that four-stranded ‘quadruple helix’ DNA structures – known as G-quadruplexes – also exist within the human genome. They form in regions of DNA that are rich in the building block guanine, usually abbreviated to ‘G’.