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Startup companies have traditionally looked for the most experienced venture capitalists they could find to get their businesses off the ground and support their growth. That’s not always the case anymore, according to a study by University of Maryland Robert H. Smith School Associate Professor Rich Mathews and his co-author Naveen Khanna of Michigan State University. They argue that startups straight out of the gate are often deciding to work with new venture capitalists rather than established ones.

 

The University of Maryland Medical Center in Baltimore.

(Photo by Flickr user Baltimore Heritage, used via a Creative Commons license)

One of Maryland’s premiere medical networks just announced an eight-figure investment into the economic development of local and marginalized communities by way of notable funding entities.

The University of Maryland Medical System (UMMS) said in a Thursday statement that it will commit  $14 million to  11 community development financial institutions and privity equity firms throughout the state. The investment is intended to address racial, economic and environmental disparities in the communities the system serves.

Image: The University of Maryland Medical Center in Baltimore. (Photo by Flickr user Baltimore Heritage, used via a Creative Commons license)

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CHARLOTTESVILLE, Va., Sept. 15, 2022 /PRNewswire/ -- AMPEL BioSolutions today announced a breakthrough in precision and personalized medicine that can detect and predict the severity of COVID-19 in patients while also determining the best treatment options for each specific case. The company's new approach, through a simple blood test, will ultimately accelerate the means of providing effective treatments to the right people at the right time and potentially stem the serious illness caused by SARS-CoV-2 infection that can lead to lung damage or death.

AMPEL's new genomic test, known as CovGENE®, has been validated by a longitudinal study in partnership with physicians in the Division of Pulmonary and Critical Care Medicine of the University of Virginia Medical Center. With careful analysis of patients admitted to the UVA Intensive Care Unit, CovGENE® demonstrated remarkable precision with a greater than 90-percent rate of accuracy. CovGENE®, can be administered by drawing a patient's blood to quickly ascertain whether a Covid-19 patient will have a mild, moderate, or severe outcome. The findings are detailed in a paper published today by Frontiers in Immunology.

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Waltham, Mass. and Dublin – August 15, 2022 — Q32 Bio, a clinical stage biotechnology company developing biologic therapeutics to restore immune homeostasis, and Horizon Therapeutics plc (Nasdaq: HZNP), today announced that they have entered into a collaboration and option agreement to develop ADX-914 for the treatment of autoimmune diseases.

ADX-914 is a fully human anti-IL-7Rα antibody that re-regulates adaptive immune function by blocking signaling mediated by both IL-7 and TSLP. Q32 has recently completed a biomarker-enabled Phase 1 study characterizing pharmacokinetics, pharmacodynamics and safety of ADX-914 that demonstrated pharmacological effect on T cells in healthy volunteers. Q32 expects to initiate a Phase 2 trial in atopic dermatitis later this year and is planning to initiate a Phase 2 trial in a second autoimmune disease next year.

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La Vista, Nebraska — September 14, 2022 – Streck announced today a Series B investment in Ceres Nanosciences (Ceres). The funds from this investment will be used to accelerate the development and commercialization of both diagnostic and research use products utilizing Ceres' Nanotrap® technology platform.

"Streck has a deep presence in and knowledge of the diagnostics industry and shares our commitment to building long-term relationships with partners and customers," said Ceres CEO Ross Dunlap. "We are thrilled to have Streck's support and guidance in this next, exciting phase of our growth."

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Swimming with Sharks pairs aspiring healthcare entrepreneurs with successful innovators and investors. The startups selected will pitch at the American Society of Anesthesiologists (ASA) Annual Meeting, ANESTHESIOLOGY®, in October 2022.

There will be two Swimming with Sharks sessions at the event: one for very early-stage startups (back of the napkin ideas/conceptual/pre-seed stage) and one for startups that are seed stage and beyond (ie series A).

 

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September 13, 2022—The Maryland Stem Cell Research Commission announced it will grant $4,165,325 in award funding to innovative research that will strengthen and advance stem cell treatments and technologies in Maryland. Awardees submitted proposals to the Commission in response to its Request for Applications (RFAs) for its first round of funding cycle in fiscal year 2023.

Recipients include 12 scientists accelerating research at Johns Hopkins University, University of Maryland, Baltimore County, University of Maryland, College Park, and the University of Maryland, Baltimore. Their research addresses an array of medical conditions, such as cancer, eye, heart, bone, blood, digestive, and immune system diseases.

 

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- The Company plans to work with the FDA to design a Phase 3 program in moderate-to-high systemic disease activity patients to begin in 2023, ahead of expectations –

DUBLIN--(BUSINESS WIRE)--Sep. 12, 2022-- Horizon Therapeutics plc (Nasdaq: HZNP) today announced that its Phase 2 trial evaluating dazodalibep for the treatment of Sjögren's syndrome met the primary endpoint in patients with moderate-to-high systemic disease activity as defined by the European Alliance of Associations for Rheumatology (EULAR) Sjögren's Syndrome Disease Activity Index (ESSDAI) score of ≥ 5. At Week 24, patients treated with dazodalibep achieved a 6.3-point reduction in their ESSDAI score and patients treated with placebo achieved a 4.1-point reduction, resulting in a statistically significant least squares mean difference of 2.2 points (p=0.017).

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The Biden administration announced the launch of a new national program dedicated to fortifying America’s biotechnology manufacturing industry in the latest executive effort to keep U.S. supply chains competitive.

Introduced Sunday via executive order, the Biotechnology and Biomanufacturing Initiative focuses on a specific biomanufacturing process that uses microorganisms to create chemicals and compounds that contribute to make medicines, fuels and other input materials.

 

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As the number of monkeypox cases around the world has ballooned since early May, so too has the list of diagnostic developers rapidly churning out tests for the virus.

Latest to join the likes of Labcorp, Roche, BD, Cepheid and others in that mission is Qiagen, which announced this week the launch of a monkeypox assay of its own. The test is designed to be analyzed by the company’s QIAstat-Dx PCR testing system.

Image: The QIAstat-Dx Viral Vesicular Panel is indicated for research use only, making Qiagen’s test available to the approximately 3,000 laboratories around the world that already have QIAstat-Dx PCR analyzers installed. (Qiagen)

Alexandria® Building the Future of Life Science™

NEW YORK, Sept. 12, 2022 /PRNewswire/ -- Alexandria Real Estate Equities, Inc. ( NYSE: ARE), the first, longest-tenured and pioneering owner, operator and developer uniquely focused on collaborative life science, agtech and technology campuses in AAA innovation cluster locations, is proud to recognize and celebrate multiple significant milestones from its position of leadership in New York City's commercial life science cluster. These milestones include (1) 20 years since Alexandria Venture Investments made its first NYC venture investment in Intra-Cellular Therapies' Series A financing in 2002; (2) 17 years since Alexandria was awarded the New York City Economic Development Corporation's (NYCEDC) request for proposal (RFP) in 2005 to develop and operate what the company has transformed into the Alexandria Center® for Life Science – New York City, the city's first and only commercial life science campus; (3) 12 years since the Alexandria Center officially opened to welcome its first tenants in 2010; and (4) five years since it unveiled the inaugural site of Alexandria LaunchLabs®, the company's world-class life science startup platform, at the Alexandria Center in 2017, which was followed by Columbia University's election in 2019 to establish a second NYC-based Alexandria LaunchLabs site on the university's medical school campus.

 

CrabTrap 2022

– Winner to be announced as part 2022 BioHealth Capital Region Forum –

ROCKVILLE, MARYLAND, September 12, 2022 – A panel of investor judges and anROCKVILLE, MARYLAND, September 12, 2022 – A panel of investor judges and anaudience of industry leaders will gather for the presentations of five early-stage companiesat the 7th Annual BioHealth Capital Region Crab Trap Competition at US Pharmacopeia onSeptember 21st in Rockville, Maryland. Created in 2016, the competition highlights thecommercialization potential of biohealth technologies throughout the region and beyond.

Click here to download the PDF

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BioHealth Innovation, Inc. (BHI) has partnered with Montgomery County, Maryland to support entrepreneurs seeking to commercialize life sciences, digital health, and medical device technologies within Montgomery County.  The new BHI-County agreement will fund one or more Executives in Residence, dedicated to cultivating the local life sciences ecosystem within Montgomery County.

Background

Over a decade ago, BHI was founded in Rockville, Maryland to coordinate and amplify the county’s existing innovation assets. Since then, our work has expanded to the BioHealth Capital Region (any beyond) by connecting life sciences, biotech and healthcare stakeholders, developing entrepreneurial talent, identifying commercially relevant federal and university technology, and attracting funding for growth-stage companies.  BHI’s original goal of raising the BioHealth Capital Region’s life sciences cluster ranking to one of the “Top 3 by 2023” is within reach.

PRESS RELEASE Gradian Health Systems Announces Partnership with Canon Virginia Inc CVI Gradian Health Systems

New York, NY, September 6, 2022 | Gradian Health Systems (Gradian) is proud to announce a strategic relationship with Canon Virginia Inc. (CVI). This announcement marks the collaboration of two mission driven organizations, with a common goal of addressing disparities within healthcare globally.

This collaboration builds on Gradian’s decade plus work developing and supporting medical technology in resource-limited settings and CVI’s 37 years of established manufacturing excellence and medical device expertise. CVI will assume manufacturing operations for Gradian’s flagship product, the UAM, an anesthesia machine designed to work in the absence of electricity and medical oxygen, and establish manufacturing operations for Gradian’s newest product – the K-O2. CVI plans to be in full scale production of both products by the end of 2022. The UAM and K-O2 are specifically designed to better enable access to anesthesia and oxygen therapy, respectively, by addressing resource constraints that often prevent medical providers from being able to deliver continuous care for patients.

 

Renee Wegrzyn will serve as the first director of the Advanced Research Projects Agency for Health.
WHITE HOUSE PHOTO

President Joe Biden plans to appoint longtime biologist and former government scientist Renee Wegrzyn as the first director of the nascent Advanced Research Projects Agency for Health.

Biden’s announcement comes as ARPA-H advocates debate where the multibillion-dollar agency should be headquartered and which elusive disease areas should be prioritized. The president officially launched the agency in March with $1 billion in initial funding allotted by Congress, but the search for its inaugural director has taken months.

Image: Renee Wegrzyn will serve as the first director of the Advanced Research Projects Agency for Health. WHITE HOUSE PHOTO