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How will protein engineering unleash a new era of therapeutic possibilities for BioHealth and the BioHealth Capital Region? Join us on this episode of BioTalk with Rich Bendis as Rich chats with Dr. Luis Alvarez, Founder & CEO of Theradaptive, who is at the forefront of protein engineering technology. Learn about Theradaptive’s ingenious approach to overcoming the challenges of naturally occurring proteins, elevating the efficacy and safety of therapeutics through precision-targeted delivery, and mitigating off-target side effects. From spinal fusion and orthopedics to soft tissue repair and targeted chemotherapeutics, Theradaptive’s breakthrough technology is set to transform the lives of millions grappling with debilitating conditions linked to loss of tissue function. Be part of the conversation that’s unlocking a world of untapped potential in the convergence of protein engineering and therapeutic discovery. Listen now here or via your favorite podcasting platforms:

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A graduate of West Point, Dr. Luis Alvarez served in the U.S. Army for 20 years. Following a combat tour and seeing fellow servicemembers forced to undergo delayed amputations due to tissue damage, he was motivated to pursue a Ph.D. in biological engineering at MIT, where he was a Hertz Foundation Fellow. Dr. Alvarez founded Theradaptive following his time in the Army, using what he learned from his research to create a platform that can now deliver biologics in a highly targeted way. Previously, he was the founding deputy director of the U.S. Department of Defense’s Regenerative Medicine Program Office as well as lead for the DoD’s $720 million nerve agent pharmaceutical countermeasures program. As CEO and co-founder, Dr. Alvarez has seen the Theradaptive team grow from two to 32 people. The FDA granted the company three breakthrough designations for various spine indications, accelerating the process of reaching approval.

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BLACKSBURG, Va. (March 28, 2023) – The Virginia Tech Corporate Research Center (VTCRC) announced today that three companies have been selected to join Johnson & Johnson Innovation – JLABS (JLABS). Under a collaboration between VTCRC and Johnson & Johnson Innovation, LLC, established to support innovators in the Blacksburg-Roanoke region with the aim to accelerate emerging biotech and life science startups, the selected companies will have full access to JLABS programming, resources, and mentorship from experts across The Johnson & Johnson Family of Companies virtually.

Acomhal Research, Qentoros, and The Tiny Cargo Company will benefit from the JLABS global life science network and industry connections, along with access privileges to the JLABS @ Washington, DC site, while keeping their businesses located in the region.

It has been known for some time that plants communicate with one another, but Israeli scientists now say they’ve identified “words,” and have found that different species speak in different “languages,” according to a groundbreaking new study published Thursday in the prestigious scientific journal Cell.

Scientists already know that plants communicate in a variety of ways when they are stressed. They might change physically (by wilting or changing leaf color), become bitter to the taste (to deter herbivores), or emit smells (volatile organic compounds) to tell other members of the family that they are under attack, for example by insects.

Image: Tomatoes were among the plants tested for sound by Tel Aviv University researchers. (David Besa, CC BY 2.0, Wikimedia Commons)

By Tom Still

MADISON, Wis. -- Society has been here many times before. A little more than 200 years ago, a group of English textile workers called the Luddites took to destroying mill machinery -- not because they were inherently anti-technology -- but mainly to protest labor conditions at the time. The movement faded in a few years and the textile industry continued down an inevitable road to automation.

The history of technology reveals many such examples of innovation being met with suspicion and worries that mankind would lose its moral compass. From Gutenberg’s printing press to the dawn of the computer age, people have fretted that new ways and machines would erode the ability of people to discern good from bad while dangerously accelerating change.

Annapolis, Md., Apr. 3, 2023 – The Maryland Association of Chamber of Commerce Executives (MACCE) named Greater Rockville Chamber President and CEO Marji Graf its 2023 Maryland Chamber Executive of the Year.

“Marji is an exceptional leader and was selected as MACCE’s 2023 Chamber Executive of the Year because of her many notable accomplishments on behalf of the Greater Rockville Chamber of Commerce,” said Bill Chambers, MACCE President. “Marji helped the Greater Rockville Chamber, and its members deal with the many challenges of the pandemic, while still focusing on their program of work and making a difference for her members and her community.”

Among the numerous accomplishments noted in Marji’s nomination, standout achievements included diversifying and expanding her chamber’s programming, increasing its fiscal stability, and developing new, innovative responses to attracting and retaining members. “She is a dedicated
leader with a positive attitude and innovative spirit. Her commitment to the Chamber’s success was evidenced by adding new events, advocating for local businesses, and leading an effort to develop and implement values–based dues in 2022,” stated Laura Nash, Board Chair of the Greater Rockville Chamber and Relationship Manager and Vice President of West Financial Services.

An active member of MACCE, Marji is currently serving in her second year on MACCE’s Executive Board as Treasurer. Previous to moving to Maryland five years ago, Marji was a chamber leader in New England where she served as President of the Vermont Association of Chamber of Commerce Executives and President of the New England Association of Chamber of Commerce Executives.”

$600,000 invested into 3 new ventures and $1.6Million awarded to 12 project grants

COLUMBIA, Md. (March 29, 2023) – TEDCO, Maryland’s economic engine for technology companies, announced a recent round of funding through the Maryland Innovation Initiative (MII).

Established in 2012, the MII program was created as a partnership between the State of Maryland and five Maryland academic research institutions: Johns Hopkins University; Morgan State University; University of Maryland, Baltimore; University of Maryland, Baltimore County; and University of Maryland, College Park. The program’s mission is to accelerate and support the commercialization of promising technologies from bench to market through investments in innovation, entrepreneurship and venture creation. 

When husband and wife Zairen Sun Ph.D. ’98 and Beibei Li Ph.D. ’98 arrived in College Park from China in 1992, they had little understanding of their new country or its traditions or practices. What they did have was a mentor at the University of Maryland who knew what it was like to be an immigrant to the U.S.—and who could empathize with the process of adjusting to a very different way of doing things.

• NARCAN® Naloxone HCl Nasal Spray 4 mg is currently the first and only prescription strength naloxone nasal spray to receive over-the-counter status in the U.S., which is a critical step toward broadening access
• Expected over-the-counter availability is anticipated by late summer of this year

GAITHERSBURG, Md., March 29, 2023 (GLOBE NEWSWIRE) -- Today, Emergent BioSolutions Inc. (NYSE: EBS) announced that the U.S. Food and Drug Administration (FDA) has approved NARCAN® Naloxone HCl Nasal Spray 4 mg as an over-the-counter (OTC) emergency treatment of opioid overdose. This decision comes at a time when approximately every eight minutes, a person dies from an opioid overdose and research shows the epidemic is escalating in the U.S. with the rise in synthetic opioids. By offering NARCAN® Nasal Spray as an OTC treatment, anyone will be able to access it without a prescription, which is an important step in the fight to reduce the number of opioid overdose deaths occurring each day.

MARCH 28, 2023 - GAITHERSBURG, Md., (BUSINESS WIRE) -- Salubris Biotherapeutics, Inc. (SalubrisBio), a clinical-stage biotechnology company dedicated to discovering and developing novel complex biologic therapeutics, today announced it received $35 million in financing from China-based Shenzhen Salubris Pharmaceuticals Co., Ltd. The investment will be used to advance and accelerate lead candidate JK07, including the planned initiation of the first Phase 2 study in HFrEF, the continuation of the ongoing Phase 1b clinical trial in heart failure with preserved ejection fraction (HFpEF), and the launch of the Company’s first neurology clinical trial with JK07. The financing will also support the ongoing Phase 1/2 trial of JK08 in solid tumors and advance JK06, a pre-clinical biparatopic antibody-drug conjugate, into an initial Phase 1/2 study.