Howard County has plans for a new incubator that would aim to develop companies with a socially conscious focus.

The Conscious Venture Lab is a partnership between Howard County and New York-based The Porter Group LLC. The incubator, which will be housed in the county’s Maryland Center for Entrepreneurship, could begin enrolling entrepreneurs and budding startups as early as this fall.

Take Care Team Connect, an Evanston, Ill.-based IT firm that provides software platforms for population healthcare management while also offering provider coaching services on how to manage population-based workflows effectively.

Hospital executives have never been frivolous when it comes to investing in technology, but as reimbursements shrink, the need to carefully analyze each purchasing decision has never been more urgent. Given all the worthwhile – and not so worthwhile – options, what choices are hospital administrators currently making?

Washington: A group of researchers have made a significant breakthrough for figuring out which mutations are benign and which are deleterious in cystic fibrosis.

BioMaryland is supporting various events in France which benefit the biohealth community. See if your company qualifies for a travel assistance grant to fly out and attend!

This summer marked the inauguration of the DreamIt Health accelerator, a startup boot camp focused on healthcare IT run by DreamIt Ventures and powered by Penn Medicine and Independence Blue Cross. In four short months, ten extraordinary teams of entrepreneurs, including four from Wharton, were brought together from around the country to achieve significant milestones going from concepts to prototypes, products, pilots and revenues. As the program wound down, the investor, startup and healthcare community turned out in force for Demo Day to see a snapshot of each company's progress and plans for the future.

AstraZeneca today announced that MedImmune, its global biologics research and development arm, has entered into a definitive agreement to acquire Amplimmune, a privately-held, Maryland, US-based biologics company focused on developing novel therapeutics in cancer immunology.

Investigators discuss new findings in Biomedicine and Biomedical Engineering. According to news reporting out of Baltimore, Maryland, by NewsRx editors, research stated, "Case reports document successful use of a high-density polytetrafluorethylene membrane to augment horizontal defects associated with immediately placed implants."

Our news journalists obtained a quote from the research from the University of Maryland, "This membrane, which is designed to withstand exposure (not require primary closure) to the oral cavity because it is impervious to bacteria, reduces the need for advanced flap management to attain primary closure. Thus, the surgical aspect is less complex and the mucogingival architecture of the area can be maintained."

Biomedical engineers from The Johns Hopkins University have partnered with clinicians to create new therapeutic eye injections for a type of central vision loss caused by blood vessel growth at the back of the eye.

The new drug, with a biodegradable time-release coating is currently being tested to evaluate effectiveness in stopping such growth in mice.

Punit Dhillon built his career arranging Canadian venture capital funding for life sciences research and running companies that performed clinical trials in Canada.

Yet when he co-founded a company to develop cancer treatments two years ago, the president and chief executive officer of San Diego-based OncoSec Medical Inc. found he had no option but to operate solely in the United States.

Renee M. Winsky, a Maryland business executive with broad experience leading organizations, was named Leadership Maryland’s president and CEO.

She will replace Nancy Minieri, who founded the organization in 1992 and announced in March that she will retire at the end of this year.

Hospital executives have never been frivolous when it comes to investing in technology, but as reimbursements shrink, the need to carefully analyze each purchasing decision has never been more urgent.

Given all the worthwhile – and not so worthwhile – options, what choices are hospital administrators currently making?

Since IT spending is largely taken up by meeting meaningful use and ICD-10 requirements, said Chantal Worzala, director of policy at the American Hospital Association, hospitals don’t have much left over for investments in other things.

American healthcare workers' confidence levels remained fairly consistent in the second quarter of 2013, according to the Q2 Randstad Healthcare Employee Confidence Index. Confidence levels among healthcare workers decreased by one-fifth of a point, to 54.3, in the second quarter of 2013.

Harris Interactive conducted the online survey o behalf of Randstad Healthcare in April, May and June of this year, among 188 healthcare workers, ages 18 and older. It included physicians, healthcare administrators, healthcare IT professionals and other healthcare professionals.

What if we could increase productivity and stave the capital flight by helping Life Sciences startups build their companies more efficiently?

We’re going to test this hypothesis by teaching a Lean LaunchPad class for Life Sciences and Health Care (therapeutics, diagnostics, devices and digital health) this October at UCSF with a team of veteran venture capitalists.

You sit down to a family dinner with aunts, your grandmother, three second cousins once removed, a floating niece, maybe a family dog. You’ve got great news: You’ve been accepted to Johns Hopkins University, a school that people who don’t live in the mid-Atlantic region know about, a school foreigners desperately want to get into. It’s ranked 13th in the world by the most recent U.S. News and World Report, for God’s sake; it’s definitely time to celebrate.

Your whole family remembers hearing Hopkins’ name in that Prince and Me movie with Julia Stiles, where she wanted to be a doctor instead of just marrying a prince and being rich and stuff. I guess that’s kind of what Hopkins is about, the whole getting educated and doing things instead of marrying a rich dude thing (though, who knows, there are a lot of future engineers/doctors around).

GlaxoSmithKline plc, a research-based pharmaceutical company, recently announced the U.S. Food and Drug Administration’s approval of GSK’s FluLaval Quadrivalent influenza virus vaccine for individuals three years of age and older.

The vaccine is the second GSK intramuscular quadrivalent influenza vaccine approved by the FDA, following the approval in December of GSK’s Fluarix Quadrivalent. FluLaval Quadrivalent protects against two influenza A strains and two influenza B strains. Previous vaccines only included three strains to protect against two A virus strains and one B strain.

Corporate venture capital may be what fills in the large gaps VC has left behind, with CVC deals about 60 percent larger than VC deals on the whole.Healthcare corporate venture capital deals are up nearly 40 percent compared to Q1 and funding is up 34 percent, according to a report from CB Insights.

There were 126 CVC deals in Q2, ringing in at a combined value of $1.7 billion. Of these deals, 40 percent were at Seed or Series A-level, meaning CVCs may be willing to take risks VCs aren’t any more. According to the report, CVCs may help companies escape the Series A crunch: “One of every 4 CVC deals in Q2’13 were Series A deals ’ this represented an 800 basis point increase in Series A deal share vs. Q2’12.”

Howard County is teaming up with Johns Hopkins University to launch a new accelerator geared toward commercial technology.

The new accelerator, called the Accelerator for the Commercialization of Technology, will help bring to market technology developed at the massive Hopkins Applied Physics Laboratory in Laurel. Howard County Executive Ken Ulman plans to formally announce the new partnership between the laboratory and the Howard County Economic Development Authority at an event Thursday.

The Office of Technology Transfer (OTT), Office of the Director (OD), the National Institutes of Health (NIH), invites industry organizations (including corporations, partnerships, limited partnerships, and industrial development organizations); public and private foundations and nonprofit organizations to solicit research proposals from scientists across the NIH Intramural Research Program (IRP) for multiple focused research projects under a the NIH Cooperative Research And Development Agreement (CRADA) Program. This CRADA Program is an extension of collaboration opportunities solicited by NIH or developed on a one-on-one basis. As such, it is consistent with PHS Technology Transfer policy and the public health mission of the NIH. These collaboration opportunities are structured under the authority of 15 U.S.C. 3710a—Cooperative Research and Development Agreements. Note that the CRADA mechanism does not permit the transfer of funds from the NIH to a collaborator but does permit the collaborator to provide funding to the NIH researcher.

CareFirst BlueCross BlueShield has jumped head-first into the deep waters of mobile health. The health insurance giant has selected Cognizant, a mobile communication company, to provide a platform for getting mobile apps to its 3.3 million members.

Cognizant will help CareFirst offer its members "quick, secure and convenient ways" to manage their health coverage, access information about physicians and claims, and get information about benefits anytime, on any device, according to Cognizant officials in a news release.

Our partner, the Economic Alliance of Greater Baltimore (EAGB) is in the running for the Economic Development Organization of the Year. The award is presented by Baltimore Innovation Week, a celebration of technology and innovation in Baltimore.

Help EAGB reach the number 1 spot by heading over to the Awards Site and and selecting Economic Alliance of Greater Baltimore in category 4, Economic Development Organization of the Year.

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Rockville-based Emergent BioSolutions Inc. on Friday announced the appointment of Barry Labinger, a well-known former executive at Human Genome Sciences Inc., to head its biosciences division.

Labinger served as HGS' chief commercial officer from 2005 until last year, when GlaxoSmithKline plc snapped up the Rockville drug-maker for $3.6 billion. Glaxo made a clean sweep of Human Genome executives, including CEO Tom Watkins, shortly after.

Thursday, August 22, 2013 10:00 am

This webinar, hosted by GUIRR, will present a new resource, the Federal Laboratory Consortium (FLC) Available Technologies tool. The tool provides a free, one-stop shop to locate licensing opportunities for a particular technology anywhere within the FLC's nationwide system of federal labs and research centers. Fully equipped with Google’s advanced search capabilities, the FLC Available Technologies tool yields user-friendly results that can be saved, printed, or downloaded as a PDF with active hyperlinks that directly link to the featured technology.

Industry and academic representatives who would like to find out more about how this tool can reduce the time, effort, and guesswork needed to find federal laboratory inventions available to transfer are encouraged to participate.

Through the Advanced Studies in Technology Transfer program, students will simultaneously gain the necessary knowledge and build professional networks with respected practitioners of the field. Our objective is to serve not only the needs of scientists and engineers who wish to pursue this non-traditional career, but also those of professionals who seek additional training.

View available courses in the Advanced Studies in Technology Transfer program.

More Information

The relatively new field of Technology Transfer can trace its origins and rapid growth to the economic developments and legislation of the early 1980s, a time when the US was looking to enhance its global competitiveness. While countries like Germany and Japan were exceptionally good at translating the ideas that originated from academic labs into useful products, US academic research results were by and large relegated to mere publications in scholarly journals. Concerned about the non-use of this potential goldmine of ideas, the US lawmakers passed a series of legislation in the early 1980s culminating in the famous Bayh-Dole Act. This Act has shifted the onus of commercialization from a central granting agency to the numerous grantees that receive the research funds, and the grantees have taken very enthusiastically to this shift. The Economist has lauded this Bill as the most inspired piece of legislation in the last half century.

In the middle of 2003, Marc LaForce was having trouble sleeping. As the director of the Meningitis Vaccine Project (MVP), he was missing a vital piece of a difficult puzzle. The MVP sought to commercialize a vaccine that would help prevent Africa’s devastating epidemics of meningococcal meningitis, a bacterial infection of the brain and spinal cord. The largest documented outbreak, in 1996, sickened 250,000 people in Africa and caused 25,000 deaths. In 2002, a single West African country (Burkina Faso) had 13,000 meningitis cases and at least 1,500 deaths.

To succeed, the MVP needed a vaccine production method with two essential qualities: very effective and very affordable. But in mid-2003, that search hit a dead end. "All projects have their ups and downs," says LaForce, M.D. "We were in the downest of downs."

This week, FDA issued final guidance on incorporating and integrating radio frequency wireless technology into medical devices, Bloomberg BNA reports.

In a blog post on Tuesday, FDA Senior Policy Adviser Bakul Patel wrote, "Our goal is to help industry develop a range of innovative, safe and effective medical devices that incorporate wireless technology, which can, in turn, help reduce health care costs, enhance quality and benefit patients and providers alike" (Weixel, Bloomberg BNA, 8/14).

The new landscape for venture capital investing does not seem to leave much room for classic company formation. Investor after investor has shut down or moved beyond startups into what seem like greener pastures.

So it should come as no surprise that at least a few VC firms are now expanding into the royalty space, as shown by a deal announced this week. Aisling Capital and Clarus Ventures, two top-tier VC firms, acquired 20 percent of the royalty stream created by sales of ibrutinib, a novel tyrosine kinase inhibitor developed by Pharmacyclics (NASDAQ: PCYC) and partnered with Johnson & Johnson (NYSE: JNJ) for use in B-cell malignancies such as chronic lymphocytic leukemia (CLL).

With the global tuberculosis epidemic becoming more deadly, costly, and difficult to treat, Chinese Center for Disease Control and Prevention (China CDC) and Aeras today signed a memorandum of understanding to advance research and development of new tuberculosis vaccines. An improved TB vaccine offers the best hope for eliminating this airborne infectious disease that kills 1.4 million people worldwide each year.  

While China has achieved significant reductions in TB illness and death over the past 30 years, TB remains a major public threat, with over one million new cases in China each year. A study published in the New England Journal of Medicine last year found that one in 10 cases of TB in China are resistant to the most commonly-used drugs. Based on the World Health Organization’s estimates of global multidrug-resistant TB (MDR-TB), China has the highest annual number of cases of MDR-TB in the world—a quarter of the cases worldwide.

DreamIt Health Demo Day has gotten a lot of great press, from Philly.com to NewsWorks to Technical.ly Philly, and many more. These plaudits are well deserved: DreamIt Health was the first Philadelphia-based health care accelerator, and by all accounts it was a huge success. Ten health care startup companies participated in this venture, made possible by a collaboration between Independence Blue Cross (IBC), Penn Medicine, and DreamIt Ventures. The more than 300 attendees to the Demo Day on July 24, 2013 included potential investors and customers, mentors, and health care executives.

We at Wharton Entrepreneurship are delighted, and not only because this event was such a terrific demonstration of the robust community of heath care entrepreneurs in the Philly region. We’re proud to point out that the founders of four of the presenting companies and both of the speakers are all Wharton Entrepreneurship alumni, several of whom went through our Venture Initiation Program (VIP)! If that’s not a demonstration of Knowledge in Action, then I don’t know what is.

Let’s Celebrate How Baltimore Is Innovating.

The people and organizations represented below are advancing the city in new and inspiring ways, by growing businesses, increasing regional economic activity, publishing high-quality works of media, creating new gateways to the technology community and much, much more. They’re the best of the best in this community. This is the Baltimore region’s only people’s choice award for technology, entrepreneurship and new thinking.

Winners will be determined by online voting counts. Voting closes on Friday, September 13th. Awards will be announced at the Baltimore Innovation Week week closing party on Fri. Sept. 27.

Due to the global shortage of donor hearts, patients on the waiting list for a heart transplant can wait several months to several years for a match to be found. But for 36-year-old Frédéric Thiollet, who surpassed two years of support with the SynCardia temporary Total Artificial Heart on Aug. 5, he’s enjoying each and every day.

“I feel well and I am confident, having been implanted now for over two years,” said Frédéric Thiollet. “I have recuperated all my physical functions, even my sexual activity, which I had believed was gone forever. In my own words, I have enjoyed an effective resurrection, a new birth. Physically I have no limit. I am as strong and powerful as before, even more so than before.”

Funding and Research Opportunities

The following funding opportunity announcements from the NHLBI or other components of the National Institutes of Health, might be of interest:

NIH Guide Notices:

• NOT-OD-13-098: Grant and Contract Submission Requirements Regarding the AVMA Guidelines for the Euthanasia of Animals: 2013 Edition 
• NOT-HG-13-014: Request for Information (RFI): Input on Development of Analysis Methods and Software for Big Data 
• NOT-HL-13-185: Notice of Intent to Publish a Funding Opportunity Announcement for a Coordination Core for Programs to Increase Diversity Among Individuals Engaged in Health-Related Research (PRIDE II) - (R25)
• NOT-HL-13-189: Notice of Availability of Specimens and Data for Hemochromatosis and Iron-Related Research 
• NOT-HL-13-190: Notice of Expiration of PAR-11-090 NHLBI Investigator-Initiated Resource-Related Research Projects (R24)

Request for Applications (RFA):

• RFA-RM-13-006: 2014 NIH Pioneer Award Program (DP1) 
• RFA-RM-13-007: 2014 NIH Director's New Innovator Award Program (DP2) 
• RFA-RM-13-012: NIH Health Care Systems Research Collaboratory - Demonstration Projects for Pragmatic Clinical Trials Focusing on Multiple Chronic Conditions (UH2/UH3)
• RFA-RM-13-018: DNA Sequencing Core for an Undiagnosed Diseases Network (UDN) (U01)

Program Announcement (PA):

• PAR-13-316: NHLBI Program Project Applications (P01)

The University of Maryland College Park, which likes to tout itself as a leading public research institution, has added a little more green to its laurels.

Sierra Magazine ranks the state's flagship campus as the 13th greenest university in its latest national rating of "Cool Schools."

UM trailed the University of Connecticut, Dickinson College, Stanford and American universities, among others, while besting the likes of Harvard, Yale and the University of California, Berkeley.

XLerate Health, a Louisville-based accelerator for early-stage, health-related companies, has selected six companies to participate in its inaugural class. The accelerator’s 10-week intensive immersion program began Monday and runs until “Demo Day” on Oct. 25.