MedImmune, the global biologics R&D arm of AstraZeneca, is always enthusiastic about explaining how its science benefits patients’ lives. So taking part in Cambridge’s highly successful Science Festival, which finished last weekend, is a wonderful opportunity for the company to reach out and share its activities with the wider Cambridge community.   

With many thousands of visitors, the Cambridge Science Festival provides the public with opportunities to explore and discuss topics of scientific interest and, importantly, is the perfect place to raise aspirations by encouraging young people to consider a career in science. Over both weekends of the Festival, firstly in the Corn Exchange and then at the Clinical School at the Cambridge Biomedical Campus, over 35 MedImmune scientists volunteered their time to demonstrate to a continual stream of visitors to understand how new antibody medicines are found using viruses which grow in bacteria.

Contract research organizations make good money providing critical services to young biotech and drug development companies early on. But often, those companies are cash-strapped at the stage when they need a CRO. That’s why some CROs are becoming stakeholders in the companies they work with, offering cash or services for equity in life science startups.

“We fundamentally believe that we should be aligned with our clients,” said David Gee, strategic business development at Cato BioVentures, the venture capital affiliate of a CRO called Cato Research. “I think it’s reasonable, particularly with early-stage companies, that we have some skin in the game. (Then) we have reason to come to a positive endpoint and to get there as quickly and efficiently as possible, because that’s how part of our value is going to be generated.”

The Maryland Department of Business and Economic Development (DBED) announced today that 12 startup companies have advanced to the final round of the InvestMaryland Challenge, the State’s national business competition. The finalists are competing for $100,000 top prizes in four categories — Information Technology, Life Sciences, General Industry, and, new this year, Cybersecurity. All companies who entered the Challenge are eligible for more than $300,000 in other prizes, including grants, software and lab and incubator space. The winners will be announced in May.

“Congratulations to the finalists and all the companies that advanced in the InvestMaryland Challenge. To stand out from the field of 260 applicants is an achievement in itself and a testament to the strength of the companies competing for the top prizes,” said Dominick Murray, DBED Secretary. “For two years in a row, Maryland has been named the #1 state in the country for innovation and entrepreneurship and companies like those competing in this Challenge are the reason why. They are the future leaders of Maryland’s Innovation Economy and we are proud to support them as they grow and create jobs.”

For startup CEOs, there’s probably nothing more nerve wracking than giving a presentation to prospective investors. Dr. Lisa Beth Ferstenberg knows about that first-hand.

A serial biotech entrepreneur, Ferstenberg was founding CEO of Cellective Therapeutics, a Gaithersburg biotech that raised $28 million in Series A funding. MedImmune bought the company in 2005 for as much as $160 million. She is currently chief medical officer for Sequella Inc., a Rockville biotech that develops drugs to fight tuberculosis.

Europe has shown the world over the past half century how countries with centuries of conflict can finally cast aside their differences and work together. The European Union has created a single currency, a common patent office, a single public funding source for basic research, and a single legislative body for issues reaching across the continent.

But if there’s one area where the countries of Europe continue to compete vigorously—other than in soccer and other sports—it’s in their efforts to attract and build up communities or “clusters” of biotechs, pharmaceutical employers, universities, and independent research institutions.

Seth Goldman and Barry Nalebuff founded Honest Tea in 1998. In the recently released Mission in a Bottle, the co-founders tell -- in comic book form -- the story of building a successful mission-driven business. Goldman, now president and "TeaEO" of Honest Tea, joins Motley Fool CEO Tom Gardner to discuss sustainability, entrepreneurship, and what it means for a socially responsible, health-oriented business to be bought by Coca-Cola  (NYSE: KO  )  .

In addition to his work with Honest Tea, Goldman co-founded Bethesda Green to help green businesses get off the ground, and has been involved with healthy food companies Beyond Meat and Happy Baby. 

As a direct result of Montgomery County's ongoing partnership with Chungbuk Province, which includes a Chungbuk Exchange Official who has worked at DED since February 2013, three Korean companies have launched U.S. operations at the County's Germantown Innovation Center (GIC).

“The greatest danger in times of turbulence is not the turbulence; it is to act with yesterday’s logic.” Peter Drucker

In a period of massive change, franchises die and are born, previously unimagined models emerge, and incumbents that are too focused on “protecting share” find themselves closing their doors. The healthcare industry represents nearly a fifth of U.S. GDP and it is going through such a period of dramatic change as we speak.  The product companies that dominate the marketplace today find themselves cash rich but growth poor.  At the same time an army of inventors and visionaries in biotechnology, medical devices, diagnostics, health care services, healthcare IT, and consumer health fields are eager to provide a new model for the future.

Ambient Clinical Analytics is a new startup, founded by Mayo Clinic researchers with help from Silicon Valley investors, that aims to bring data assimilation, communication and analytics to the bedside.

Backed by Rock Health and the Social+Capital Partnership, the venture develops decision support tools for intensive care units, operating rooms and emergency departments. Its technologies, which were developed at the Mayo Clinic, enable real-time access to process-of-care information and analytics.

Thursday, May 8, 2014 from 9:00 AM to 5:00 PM (EDT)

Learn from leading investors on syndication:

• Richard Anders, Mass Medical Angels
• Barbara Fox, Avaxia Biologics
• Henry Kay, Launchpad Venture Group
• Reid Leonard, Merck Research Ventures
• Mike McGrail, Cooley LP
• Moderator: Stephen Flaim

Connect with 23 NHLBI companies seeking early-stage investors and partners

• Discover innovative technologies close to commercialization
• Attend a reception to partner and network

Registration is free, but space is limited. Sign up now to save a spot!

More information and agenda to follow.

The Hive is an immersive and informal social environment, dedicated to exploring and showcasing transformative startups and the inspiring entrepreneurs that power the ideas shaping the future of health and medicine.

Our second location will allow us to host The Hive on both coasts – increasing the number of game-changing startups who will join us this coming September 10-12 in either Washington, DC or San Francisco, CA. To help support a growing community of Hive entrepreneurs, we’re re-opening the Hive Application process for two short weeks and applications will be accepted today until April 1.

New Enterprise Associates is up to its neck in initial public offerings these days. But even for NEA, a chipmaker IPO isn't exactly common.

One of the Chevy Chase-based venture capital firm's portfolio companies, Milpitas, Calif.-based Aquantia Corp., this week  announced a $16 million Series G financing led by Xilinx Inc., a possible prelude to a public offering for the decade-old semiconductor company, an executive  told The Wall Street Journal.

More than 21 startups presented their technology offerings to Exelon executives and IT employees at "Dancing with Startups," a two-day event hosted by Exelon and the Economic Alliance of Greater Baltimore at the University of Maryland, Baltimore County, and the Cyber Point Technology & Innovation Center last week.

The event is part of Exelon's continuing effort to reach out to technology innovators in search of new ideas that have the potential to transform the energy industry. From cybersecurity software to smartphone technology, participating companies pitched their ideas and products during rapid-fire, 20-minute sessions. Exelon employees peppered the groups with questions, seeking to identify new technologies that Exelon might be able to pilot.

People who are prone to bleeding due to poor blood clotting, such as those with hemophilia or on anticoagulants, are often required to take blood tests. These test are usually done in clinics and hospitals, adding to the patient’s burden and expense of extra travel just to make sure that blood is adequately anticoagulated. New technology that is being developed at Qloudlab, a startup based at École polytechnique fédérale de Lausanne (EPFL) in Switzerland, uses capabilities already present in today’s smartphone screens for blood coagulation testing.

Video games have been used in a number of therapeutic applications, such as managing pain in burn victims and helping youngsters deal with depression. A new project in Australia is bringing together video game technology with gesture recognition and some other components to create a virtual reality interactive environment for dementia patients and their caretakers. The project is still in the development stage, and is looking for crowdsourced funds, but the video below shows off the current prototype that will eventually include a 10 m x 10 m projection screen, a touch display, and special lighting.

Pharmaceutical companies have long relied on successfully launching new drugs to drive growth. This pressure is only likely to increase. Patents are expiring and product pipelines are shrinking. Austerity measures in many countries are increasing local and national hurdles for market access. And, at the same time, launches are becoming more numerous, smaller, and more competitive. We estimate that pharmaceutical companies will launch some 400 new products in the next three years, up 146 percent from 2005. Given this changing external landscape, awash with more products of ever greater diversity, it’s never been more important for pharmaceutical companies to crack the new-product launch code.

The University Economic Development Association (UEDA) is currently seeking nominations for its annual Awards of Excellence program, which recognizes cutting edge university-based economic development initiatives from across the country. The Awards of Excellence Program recognizes higher education institutions and their partners who are transforming their campuses into engines of economic prosperity through creative initiatives in five categories:

Don't take $5,000 from all your friends, Fortify Ventures Managing Director Jonathon Perrelli warns a founder over lunch in the second episode of “Startupland,” or "you're going to have 20 pains in the asses."

If “Startupland” — a documentary on early-stage entrepreneurship that premiered last week in D.C — does one thing well, it's depicting the complex and uneasy relationship founders have with outside capital. The above quote, in particular, is a particularly blunt reference to the pitfalls of the friends-and-family round, where a startup CEO risks adding a horde of impatient, inexperienced micromanagers to his cap table. It's a tension that runs throughout the first two episodes of “Startupland,” which was screened on March 13 at Landmark's E Street Cinema. Founders need early money, yet early money is expensive.

Small technology companies could get help hiring interns through a proposed program aimed at strengthening ties between businesses and universities.

Under a General Assembly bill, the Maryland Technology Internship Program would give 40 small businesses up to $3,000 a year to hire interns. The bill (HB1317) to create the program was approved by the state House of Delegates and is being considered by the Senate. If approved, Gov. Martin O’Malley would need to authorize funding for the program, estimated at $190,000 in fiscal 2015.

Commercializing technology doesn’t have to be all about patents, licenses and startups.

Universities looking to grow their influence in the technology sector often focus on patenting their own ideas, starting companies from faculty research and other strategies that keep new ideas in-house or on a leash. But Maryland’s technology industry relies on the talent coming out of local universities. And in order for the industry to grow and thrive, technology companies and universities will need to forge stronger bonds.

According to financial services firm Ernst&Young, global venture capital investment in 2013 increased 2 percent compared to 2012, to $48.5 billion. Meanwhile, economic conditions improved in many geographic markets due to increased levels of liquidity and a boost in investor confidence.

The upshot: More investors are competing to invest in promising startups and entrepreneurs, especially outside the U.S.

2014 will continue to be a year of transformation as the implementation of the Affordable Care Act and the changes it represents ripple through the healthcare industry. From conversations with healthcare providers across the country, Vree Health has identified four key issues providers face in the coming year–and beyond.

1. Healthcare reimbursement is due for a reboot

Healthcare systems, hospitals and providers are caught between two widely divergent business models: fee-for-service versus pay-for-performance. While dependent on the former, they must restructure their businesses to improve quality and manage costs across the entire care continuum to prepare for the latter. It’s an about face that Dr. David Nash, Founding Dean of the Jefferson School of Population Health, likened to turning an aircraft carrier around in the Panama Canal, when he spoke at MedCity CONVERGE last year.

Last year the California HealthCare Foundation (CHCF) put out a report on healthcare accelerator programs that we covered at the time. It is still the best summary of the health accelerator space. CHCF also created an infographic on how healthcare accelerators can maximize their value. The report focused on Rock Health, Startup Health, Blueprint Health, HealthBox, StartX Med, and TigerLabs.

Since that report was published, other health accelerators have launched and had classes, DreamIt and Wildcatters being the largest ones that come to mind. The accelerator landscape is getting attention right now with SXSW going on and accelerators are active at and around conferences. I thought it was time to revisit the subject.

The Tech Council of Maryland (TCM), Maryland's largest technology trade association, is pleased to announce that three members of its board have been named to a statewide private sector economic development commission. They are Douglas Doerfler, CEO of MaxCyte and TCM chairman; Dr. DeRionne Pollard, president of Montgomery College; and Christy Wyskiel, senior advisor for Enterprise Development at Johns Hopkins University.

AstraZeneca's global biologics R&D arm MedImmune and the University of Cambridge have entered into a three-year oncology research collaboration in order to advance cancer research by using imaging technologies to measure key biologic changes within growing tumors.

COLLEGE PARK, Md. — The $100K ACC Clean Energy Challenge, a business plan competition supported by the Department of Energy's (DOE) Office of Energy Efficiency and Renewable Energy (EERE) encouraging students from universities in the southeastern United States to develop business plans for new clean energy companies, today announces its Elite Eight Plus Two, with nine winners from ACC schools and one winner from the at-large, non-ACC pool of entrants.

University of Maryland students will host Bitcamp, the university's first Major League Hackathon, April 46, 2014 in Cole Field House on the university's College Park, Md., campus. More than 750 college and high school students from across the country are expected to attend the innovative technology summit at UMD.

The University of Texas MD Anderson Cancer Center and MedImmune, the global biologics research and development arm of AstraZeneca, will collaborate through MD Anderson's Moon Shots Program to develop therapies that unleash patients' immune systems to attack their cancers.

Perhaps one of the most persistent struggles when dealing with anxiety is what people get wrong about the disorder.

According to Joseph Bienvenu, an associate professor of psychiatry and behavioral sciences at Johns Hopkins University, there are many fallacies when it comes to anxiety disorders, and that can make dealing with it more difficult. These misconceptions are a common reality for those who either have the condition, know someone who is battling it or think they may be on the brink of a diagnosis. We've debunked the 10 of the most common myths about anxiety and panic disorders.

Every day on my way to work, I walk past the “Deepthroat Garage,” the once-secret spot where The Washington Post’s Bob Woodward met FBI Associate Director Mark Felt to swap info that eventually brought down President Richard Nixon in The Watergate scandal. It is a spot that resonates deeply with people in Washington, marked with a historical placard for those who are passing by.

There is another historical marker 100 feet from that location that is nowhere near as popular but arguably more significant. Across the intersection where Wilson and Clarendon boulevards meet marks the spot where the Internet was invented.

Imagine a world in which everyone is empowered to take charge of their own health care by discovering their personal genetic risk factors. That's the vision of Anne Wojcicki, founder and CEO of the personalized gene-testing company 23andMe.

"How many people love the health care they're getting today?" Wojcicki asked a large audience here Sunday (March 9) at the South By Southwest Interactive festival. Only a handful of people raised their hands.

Health technology startups shone this year at South by Southwest Interactive.

Pedicab bikers raved about TumorPaint (the inventor of the “molecular flashlight” delivered a rousing talk), and Misfit Wearables piqued excitement by giving out 100 of its free fitness devices to attendees. And a mental health startup called ThriveOn beat out social networking apps to win Best of Show at the accelerator competition.

Here’s a testament to how 3D printing is making rapid prototyping more accessible to startups and entrepreneurs. Pictured here is a smartphone case designed and 3D printed by 15-year-old Suman Mulumudi, a student at Lakeside School in Seattle (where Bill Gates attended).

Mulumundi is also the CEO of Stratoscientific, a company he co-founded with his father, a cardiologist, to commercialize the case and another cardiology device he developed.

Featuring Chris Sasiela, PhD, RAC, Regulatory Strategist, Office of Translational Alliances and Coordination, NHLBI, this inaugural Hangout, “Navigating the FDA website,” will provide biomedical innovators with an overview of the types of information available on the U.S. Food and Drug Administration website including: organization charts, contact info, guidance documents, and more!   Key take-away points will include: -A guide to finding organization charts for the FDA’s Center for Devices and Radiological Health, Center for Drug Evaluation and Research, and Center for Biologics Evaluation and Research -Contact information for various Offices and Divisions -Contact information for Small Business Assistance contacts -Guidance documents -Public information related to product approvals that can be applied to your technology   Tune in and share out using the hashtag #SBIRChat .

MIT professor Yael V. Hochberg revealed the most effective startup accelerators in the country Tuesday at SxSW in Austin. DreamIt Health showed up in slot #15 and was the only health focused accelerator on the list.

Hochberg is a professor of Finance at the Sloan School of Management at the Massachusetts Institute of Technology. She and professor Susan Cohen of the University of Richmond and the Batten Institute at the University of Virginia’s Darden School of Business, used original research and data from CrunchBase to rank the 15 accelerators.