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Brace Pharmaceuticals Inc., an arm of Brazilian pharma company EMS S/A, has established its U.S. headquarters in Rockville and will invest $200 million in the operation, the O'Malley administration said Tuesday.

Brace, based out of the Rockville Innovation Center, bills itself as an "investment company" focused on developing and commercializing late-stage clinical products. It is a backer of Baltimore-based biotech Gliknik.