Big data may be about to overwhelm the healthcare system. A little healthcare business intelligence tip: Data by itself won’t drive value and outcomes. Smart healthcare analytics will. In Deloitte’s DBrief, “Big Data Revolution: Unlocking Healthcare Analytics,” healthcare industry experts talked about the opportunities and barriers for industries across the care continuum to harness data, contextualize it and use it to move from hindsight to insight (and eventually, with the help of predictive analytics, foresight).

“The future is already here,” Brett Davis, a principal at Deloitte, said. “It just hasn’t been evenly distributed yet.” Here are the six key trends in healthcare shaping how data will be used.

Have a look at a handful of the 50 events that took place during Baltimore Innovation Week 2013. Get involved with Baltimore Innovation Week 2014 here: http://baltimoreinnovationweek.com

The University of Maryland on Wednesday announced the appointment of Thomas R. Fuerst, Ph.D., as the new director of the Institute for Bioscience and Biotechnology Research.

IBBR is a joint research enterprise created to enhance collaboration among the University of Maryland, College Park (UMD), the University of Maryland, Baltimore (UMB), and the National Institute of Standards and Technology (NIST) in the fields of medicine, biosciences, technology, quantitative sciences and engineering.

British Magician Steven Frayne

The following funding opportunity announcements from the NHLBI or other components of the National Institutes of Health, might be of interest:

NIH Guide Notice:

NOT-HL-13-200: Clarification of Number of Applications to RFA-HL-14-028 "Blood and Vascular Systems Response to Sepsis (R01)"

Requests for Applications (RFAs):

RFA-HL-14-020: Evaluation and Administration Coordinating Center for the Low-Cost, Pragmatic, Patient-Centered Randomized Controlled Intervention Trials (R01)

This NIH Funding Opportunity Announcement (FOA) invites applications to support an Evaluation and Administration Coordinating Center. This unit will facilitate the coordination among and between the awardees of RFA-HL-14-019 "Low-Cost, Pragmatic, Patient-Centered Randomized Controlled Intervention Trials (UH2/UH3)" and the NIH. This unit will also be responsible for conducting an evaluation of the RFA-HL-14-019 program.

RFA-HL-14-019: Low-Cost, Pragmatic, Patient-Centered Randomized Controlled Intervention Trials (UH2/UH3)

This NIH Funding Opportunity Announcement (FOA) invites applications to plan and conduct low-cost, pragmatic randomized controlled trials (RCTs).

Using scores obtained from cognitive tests, Johns Hopkins researchers think they have developed a model that could help determine whether memory loss in older adults is benign or a stop on the way to Alzheimer's disease.

The risk of developing dementia increases markedly when a person is diagnosed with mild cognitive impairment, a noticeable and measurable decline in intellectual abilities that does not seriously interfere with daily life. But physicians have no reliable way to predict which people with mild cognitive impairment are likely to be in the 5 to 10 percent a year who progress to dementia.

An earlier research brief we’d issued highlighted that Silicon Valley dominates the list of top 50 VC-backed tech exits. The post generated a fair amount of chatter including some comments calling us arrogant Silicon Valley’ites (we’re based in NYC).

Among the more constructive comments were several from healthcare VCs who wondered if the data would be similar for the healthcare sector.  The prevailing hypothesis was that Silicon Valley’s dominance wouldn’t translate to healthcare (or perhaps not as much).  Note: our healthcare classification includes companies ranging from medical devices to biotech to pharma.

Investor Barbara Corcoran said that she has learned to spot the red flags of “well-intended misrepresentations” and fancy talk during her four seasons judging startups on Shark Tank.

Corcoran talked with Henry Blogett of Business Insider about how many companies she has invested in — about 25 — and how many have worked. Here is how she evaluated the four seasons:

Billlionaire investor Mark Cuban, who owns the Dallas Mavericks and Landmark Theaters and is a regular on Shark Tank, has expanded his interests to personalized health. He is part of a group of investors in mobile health startup, Validic,which raised $760,000 in a seed round. The Durham, North Carolina company has developed a platform to integrate and aggregate data from more than 80 health-oriented apps.

Cuban said this about the investment:

“Personalized health is the future of healthcare…and with the explosive growth of new mobile apps and devices coming on the market, Validic solves a fundamental problem of integrating all those new innovations into the healthcare system. I’m very excited for the future of Validic and the mobile health space.”

Mary Washington Healthcare (MWHC) and Zebrareach today announced a collaboration that provides MWHC's more than 4,000 Associates free membership to Zebrareach, a smartphone application that gives employees loyalty discounts at local stores, as well as other special offers negotiated for MWHC. The Zebrareach membership program for MWHC will launch in November 2013.

Zebrareach (http://zebrareach.com) is a mobile customer engagement application for small business that builds customer retention through a free consumer smartphone application. Businesses build and manage volume and tier-based loyalty programs, message exclusive news, product announcements, special events, secret menu items, limited time offers and more to their loyal customers. Customers are able to place orders for products and services through the web and mobile Zebrareach application. Zebrareach works for all customers, with or without mobile phones.

The Indian Biomedical Association (IBA) is inviting entrepreneurs from early phase companies with products or services in the life sciences industry the opportunity to connect, collaborate and partner with investors.

Entrepreneurs should submit their presentations for IBA’s event on “Developing and delivering effective investor presentation for your early stage venture” by 10/31/2013 for the event to be held on Tue November 19, 2013, 6:00 – 8:00 PM. Location: Johns Hopkins University, Room 121, Building 3, 9605 Medical Center Dr, Rockville, MD.20850

Selected companies will be invited to make their pitch to a panel of experts who will provide critical feedback.

Following the above event, a short list of selected companies will be invited to make their presentation to a group of investors on Tue December 17, 2013, 6:00 – 8:00 PM, at IBA’s “Biomedical Innovation Funding Forum“. Location: Johns Hopkins University, Room 121, Building 3, 9605 Medical Center Dr, Rockville, MD, 20850

Johns Hopkins University has an acceptance rate under 20 percent. It’s clearly a prestigious institution. But what is it like to interview for a job at the region's largest private employer?

I hit the books hard to go through Glassdoor’s index of user-submitted interview questions. Here are the three geekiest interview questions asked at Johns Hopkins (pertaining to different jobs, of course). Take a moment to see if you can answer them.

Social networks have been all “abuzz” over the past month getting the vote out for the most important elected-position in the region.  

No … silly … we are not talking about elected officials in our neighboring Commonwealth, we are talking about what really matters — the Pitch Across Maryland 2.0!!!  

Today is the day we tallied the view-votes for the “Fan Favorite” competition of the Pitch Across Maryland.

GSK has selected eight winners in its first Discovery Fast Track competition, designed to translate academic research into starting points for new potential medicines. The contest attracted 142 entries across 17 therapeutic areas from 70 universities, academic research institutions, clinics and hospitals in the US and Canada.

The winning projects show clear opportunities to deal with important unmet medical needs, including antibiotics resistance, diseases of the developing world and certain cancer types. The selected scientists will collaborate with GSK’s Discovery Partnerships with Academia (DPAc) team, the sponsor of the competition, to rapidly screen and identify novel compounds to test their promising hypotheses. If advanced chemical testing is successful, the winning investigators could be offered a DPAc partnership to further refine molecules and assess their potential as novel new medicines.

Okay. The verdict’s still out on loud. (If my family–myself included–is any indicator, that’s probably a losing battle.) The point is our human capital is plummeting globally thanks to our poor health, according to the World Economic Forum’s new Human Capital report. Our obesity and fast-paced lives are bound to catch up with us with heart disease and diabetes among other chronic disease. But it could come around and kick us where it collectively hurts the most: our already hurting economy.

View Presentation

After the trip UNN participants were interviewed and filled the Feedback forms (see the Appendix). The results of interviews and feedback forms processing may be summarized as follows.

State government agency expenditures for research and development totaled $1.404 billion in FY 2011, an 11.3% increase over the $1.261 billion reported in FY 2010. Expenditures for R&D facilities (construction projects, major building renovations, and land and building acquisitions intended primarily for R&D use) totaled $109 million in FY 2011, a 1.7% increase over the $107 million reported in FY 2010. This InfoBrief presents summary statistics from the FY 2010 and FY 2011 Survey of State Government Research and Development, sponsored by the National Science Foundation (NSF).

The FY 2010 and FY 2011 survey presents the most recent NSF statistics of R&D activities performed and funded by state government agencies in each of the 50 states, the District of Columbia, and Puerto Rico. Survey data are available by state and by individual state agency. For the first time, NSF collected two fiscal years of data from state governments as part of a single survey operation. In addition, a new category was added to this survey, so state agencies were given the option to separately classify their energy-related R&D expenditures. Other R&D categories include agriculture, environment and natural resources, health, transportation, and other.

Now on its sixth run, the Research Commercialization Introductory Course is a very popular online course designed to help science and engineering researchers better understand how research commercialization works. Over 5000 students, faculty and researchers from across the US have taken this course since it's been offered.

Research commercialization involves taking articles, documentation, know-how, patents, and copyrights, which are created during research activities and getting them to users and patients for real societal impacts. In some cases, commercialization involved taking patents based on the research and licensing them to a company. This usually involves also having the researchers consult to the company. In other cases, commercialization involves forming of creating a startup and applying to federally funded commercialization programs. In all cases, though, research commercialization typically involves defining the nature of the research being commercialized (e.g., in a patent or intellectual property agreement), establishing a commercial relationship with another party (e.g., employment, a sale or license), and negotiating a contract (e.g., compensation).

Emergent BioSolutions Inc. presented preclinical data on its lead bispecific Adaptir therapeutic, ES414, at the 5th Annual Protein and Antibody Engineering Summit (PEGS) in Lisbon, Portugal. The ES414 molecule was constructed using Emergent’s Adaptir technology platform and is being developed as a potential therapeutic for metastatic castration-resistant prostate cancer (mCRPC).

The presentation shared results of preclinical studies demonstrating ES414 is pharmacologically active and well tolerated. Preclinical in vitro and in vivo studies have shown ES414 redirects T-cell cytotoxicity (RTCC) towards prostate cancer cells expressing prostate specific membrane antigen (PSMA), an antigen commonly found on prostate cancer cells. The ES414 molecule selectively binds and links the T cell receptor on cytotoxic T cells to the PSMA on tumor cells, triggering tumor cell destruction.

Newly-minted MBA graduates are more frequently turning away from finance jobs as financial crisis aftereffects linger and instead picking careers in the tech sector.

In fact, for the first time, more Stanford Graduate School of Business grads this year chose tech jobs over finance jobs, The Wall Street Journal reports. Thirty-two percent of this year's class picked tech while 26 percent headed into finance — those figures were 13 percent and 36 percent, respectively, two years ago.

BD Diagnostics, a segment of BD (Becton, Dickinson and Company), a leading global medical technology company, announced today at EUROGIN 2013 that the Company has achieved CE/IVD marking of its BD Totalys(TM) MultiProcessor, an automated instrument that integrates the pre-processing for the BD SurePath(TM) Liquid-based Pap Test with a molecular aliquot, maintaining sample integrity while improving efficiency in the lab. The Company also supported a symposium at the conference which highlighted the performance of the new BD Onclarity(TM) HPV Assay on the BD Viper(TM) LT System, which is pending EU certification.

"These new products are part of BD's integrated Women's Health portfolio and support full sample chain of custody, high diagnostic accuracy and a clear patient management approach - all important elements to improving patient care," said Paul Holt, Global Market Segment Leader, Women's Health & Cancer - BD Diagnostics. "When laboratories and physicians partner with BD Diagnostics, they benefit from highly customized, leading-edge solutions for the rapidly changing landscape of cervical cancer screening."

Wednesday, Nov. 20, 2013, Southeastern Universities Research Association

In 2010, the University of Virginia created a pan-university innovation initiative designed to elevate innovation, entrepreneurship, and translational research as core competencies and key strategic priorities of the institution.  A long-time practitioner of “traditional technology transfer”, UVa sought nothing less than a “sea change” in its innovation ecosystem and culture in creating this new innovation platform.  Intellectual property is still protected, marketed and licensed (i.e., “traditional technology transfer”).  But beyond these activities, the university has nurtured an ecosystem (both within the institution and beyond) which can be leveraged to identify innovation and knowledge assets more broadly and earlier; to advance those assets through proof-of-principle and commercial relevance assessments; and to leverage such assets and relationships to create products, services, companies, and jobs – and value for the university.  Along the way, UVa Innovation actively uses its research capacities, social media, crowd-funding, grand challenge competitions, outreach and networking, and relentless “innovation proselytizing” to engage increasing numbers of university students, faculty, staff, administrators, alumni, and supporters in elevating innovation as core competency and focal point of UVa’s mission.

The University of Maryland BioPark announced today that the Clinical Trial Center for Functional Foods (CTCF2) has signed a lease for office space at the BioPark. The main home for the CTCF2 is located in the Jeolla-buk Province of South Korea, and is part of the Chonbuk National University Hospital.  

“When the BioPark was founded, we had the goal of establishing a strong presence from the international life sciences community,” said Jane Shaab, University of Maryland Research Park Corporation Senior Vice President and Executive Director of the UM BioPark. “We began building this presence with the SNBL Clinical Pharmacology Center, which is a wholly owned subsidiary of a Japanese biomedical company, and now we have our first investor from Korea.”

Nearly 6,000 people took part in the second annual Baltimore Innovation Week at the end of September, in partnership with many great organizations throughout the region. Full disclosure, we at Technical.ly Baltimore helped lead the big open calendar of events. Find a wrap video and some outcomes of the week below. This year, we saw […]

The Johns Hopkins University Applied Physics Laboratory (APL) will hold its second annual Parent STEMpowerment Workshop on Nov. 17, in the Kossiakoff Center on its Laurel, Md. campus. The free workshop, from 2 p.m. to 5 p.m., is designed to help parents of elementary and middle school students prepare their children to explore careers in science, technology, engineering and math (STEM).

The event, developed for parents with little or no exposure to STEM fields, will provide resources to support children in the pursuit of STEM careers and impart a better understanding of the importance of STEM.

Furthering a commitment to bilateral innovation, a delegation of five biomedical and information technology companies from the University of Nizhny Novgorod visited the University of Maryland on October 16-25 under the auspices of the U.S.-Russia Innovation Corridor.  The companies participated in the first region-to-region visit of Russian startups under the program since UMD and UNN signed a Memorandum of Understanding in April 2013 to deepen ties in the biomedical industry. 

A merger of the University System of Maryland and the Southern Maryland Higher Education Center is one step closer after leaders signed an agreement this month for a new building at the California campus.

A merger could open up educational and business opportunities for the region, officials said Friday during a signing agreement at the Chesapeake Biological Laboratory in Solomons.

The increasing digitization of healthcare could shake up the industry in many ways, from allowing doctors to do their jobs more efficiently to reducing demand for specialists, according to a new study from the Johns Hopkins Bloomberg School of Public Health.

How technological changes will increase access and improve quality of care is still a moving target, however, according to the new study, published today in Health Affairs. Meanwhile, a different set of researchers found that one technological intervention improved access to care for depression, but had no impact on depressive symptoms.

GSK today announced the recruitment of 140 new apprentices over the next two years in the UK – of which a third will be in engineering. This represents a 27% increase in the company’s annual intake of apprentices since 2012/13.

GSK also announced plans to increase the number of engineering graduate trainees by 26 in Britain – an increase of 25% since 2012/13.

DreamIt Health, a new health startup incubator that paired entrepreneurs around Philadelphia with experts from Independence Blue Cross and Penn Medicine to help commercialize new ideas, is now venturing down I-95 to expand into the city of Baltimore. We spoke with Elliot Menschik, MD, PhD, who manages DreamIt Health, about the goals of the new venture and the opportunities it plans to offer to Baltimore’s medtech entrepreneurs.

Another massive acquisition by MedImmune and a new fund to uncover the next ARM lit up a vibrant October when deals in the Cambridge UK technology cluster topped $900 million.

It took the seventh month total in Business Weekly’s Cambridge Cluster Deals Digest to just over $23 billion. While MedImmune splashed the most cash, it was a home-grown innovation that had the Cambridge investment community buzzing.

Attend the last DreamIt Health information sessions on Tuesday, November 5, 2013 from 6:00 pm - 7:00 pm at the Johns Hopkins Brain Science Institute and Wednesday, November 6, 2013 from 5:30 pm - 7:30 pm at the Johns Hopkins University Montgomery County Campus.

DreamIt Health is a health tech accelerator that helps startups achieve in four months what might otherwise take years to accomplish. The program has helped launch 130 IT companies to date.

DreamIt Managing Partner Elliot Menschik will present on November 5 and BioHealth Innovation’s Ethan Byler will present on November 6. These free programs will answer questions about Dreamit, and lite fare will be provided.

GrayBug LLC, a startup ophthalmic drug company spun out of Johns Hopkins University’s Wilmer Eye Institute, has hired its first full-time CEO and raised $1.5 million in new venture capital funding.

Michael O’Rourke, a veteran pharmaceutical industry executive and consultant, joined Baltimore-based GrayBug on Oct. 15. He comes to the company as it closed $1.5 million in funding from investors including the Maryland Venture Fund, the Abell Foundation and Brown Advisory, the Baltimore asset management firm.

Johns Hopkins Montgomery County Campus Executive Director Elaine Amir retired Sept. 30. On an interim basis, Leslie Ford Weber is serving as campus executive director.

Leslie knows her way around Johns Hopkins and Montgomery County. She is director of government and community affairs for Montgomery County, representing both the university and the Johns Hopkins health system in their interactions with county elected officials, businesses and other external organizations. Before joining Government and Community Affairs, Leslie held a dual role as executive vice president of the Suburban Hospital Foundation and senior vice president of Government and Community Relations for Suburban Hospital.