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BioHealth Innovation, Inc. (BHI), a regional private-public partnership focusing on commercializing market-relevant biohealth innovations and increasing access to early-stage funding in Central Maryland, today announced its selection of Ken Malone, Ph.D., of Early Charm Ventures, as the first BHI Entrepreneur-in-Residence (EIR) assigned to work directly with UM Ventures. Dr. Malone, a serial entrepreneur who has founded or been an officer of five biotechnology or advanced materials companies, will help advance the commercialization efforts of new start-up companies based upon innovative discoveries coming out of research programs at the University of Maryland (UMD) College Park and Baltimore.

“We’re thrilled to name Ken Malone as an EIR,” said Richard Bendis, BHI President & CEO. “Ken and I have a long history of working together, so I know first hand that he has the experience, drive and perspective to be a true asset to BHI and to the many start-ups he’ll serve from University of Maryland in support of the newly launched UM Ventures initiative.” Dr. Malone will assist any interested UM start-ups once they have been launched.

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- Technology Company Awarded Prize at Invest Maryland Challenge Ceremony -

BALTIMORE, MD, April 16, 2013University of Maryland (UM) Ventures, an ambitious joint research commercialization effort of the University of Maryland, Baltimore (UMB) and the University of Maryland, College Park (UMCP), announced today that it has awarded the first UM Ventures Start-Up Prize to VisiSonics, an Investment Maryland Challenge Semi Finalist company that was founded on intellectual property owned by the University. VisiSonics was recognized during the Invest Maryland Challenge Award Ceremony on Monday, April 15, 2013 at the Maryland Institute College of Art (MICA) in Baltimore, Maryland.

"Identifying customers and having sales is, of course, a major hurdle for university start-ups," said James L. Hughes, Director of UM Ventures, and President, Research Park Corporation, University of Maryland Baltimore. "With the significance of achieving more than half a million dollars in sales in 2012, VisiSonics is a worthy recipient of this inaugural prize."

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- Multiple SBIR/STTR Submission Deadlines Quickly Approaching -

BioHealth Innovation, Inc. (BHI), a regional private-public partnership focusing on commercializing market-relevant biohealth innovations and increasing access to early-stage funding in Central Maryland, announced today the launch of its Commercial Relevance Program (CRP). BHI's CRP is designed to help life science companies navigate the complicated process of preparing applications for federal funding, inclusive of Small Business Innovation Research (SBIR), Small Business Technology Transfer (STTR), and other federal government awards.

"The federal grant application process can be very complex. Based on 2012 data released by the National Institutes of Health (NIH), Maryland ranks 32nd out of 50 states with regard to SBIR award success rates. We would like to improve on this – and are confident that the CRP will help companies be more successful with their submissions," said Ethan Byler, Director, Innovation Programs, BioHealth Innovation, Inc.

"At the end of the day, it's about helping Central Maryland companies to get the best results possible as they seek out federal grant awards as a means of non-dilutive funding," he added.

The CRP incorporates a pre-proposal review by knowledgeable BHI staff and advisors prior to a life science company's submission of a full proposal. Through this review process, applicants will receive a set of recommendations and tips for troubleshooting their proposal for federal funding.

Interested life science companies in Central Maryland should This email address is being protected from spambots. You need JavaScript enabled to view it. today for more information. The following federal agency SBIR/STTR deadlines are fast approaching:

About BioHealth Innovation, Inc.
BioHealth Innovation, Inc., is a regional innovation intermediary focused on commercializing market-relevant bio-health innovations and increasing access to early-stage funding in Maryland. Learn more at www.biohealthinnovation.org.

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ROCKVILLE, MARYLAND, March 4, 2013 – BioHealth Innovation, Inc. (BHI), a regional private-public partnership focusing on commercializing market-relevant biohealth innovations and increasing access to early-stage funding in Central Maryland, today announced that BioHealth Innovation, Inc. President & CEO Richard Bendis is scheduled to present at the upcoming SXSW 2013 conference and the 2013 BIO International Convention this Spring. Mr. Bendis is also serving on the Program Committee for AdvaMed 2013: The MedTech Conference, which will be held in Washington, DC, in September.

Specific information for each event is as follows:

  • 2013 South By Southwest "SXSW" Conference, March 8-12, 2013, Austin Convention Center, Austin, Texas. Mr. Bendis is participating in a panel on Saturday, March 9, entitled, "Entrepreneurs-in-Residence: Not Just for VCs!" Venture capital firms have utilized the services of 'Entrepreneurs-in-Residence' (EIRs), seasoned innovators with functional expertise, to help spur entrepreneurship and fill gaps in expertise. This panel will look at the value of combining the 'innovation mojo' of EIRs with some of the government's brightest 'intrapreneurs' to solve the nation's most pressing challenges. Joining Mr. Bendis on the panel will be Arnaub Chatterjee (Associate Director of Health Information Partnerships, Merck - Office of the Chief Medical Information and Innovation Officer), John Paul Farmer (Senior Advisor to the U.S. CTO) and Zachery Jiwa, Health IT Advisor; Innovation Fellow, U.S. Department of Health and Human Services; Advisor, HIMSS State Advisory Roundtable.

  • 2013 BIO International Convention, April 22-23, 2013, McCormick Place, Chicago, Illinois. Mr. Bendis is scheduled to be part of The Translational Research Forum on April 22, 2013, beginning at 1:30 p.m., and a panel discussion focused on effective strategies in developing accelerator models beginning at 4:35 p.m.

  • AdvaMed 2013: The MedTech Conference, September 23-25, 2013, Walter E. Washington Convention Center, Washington, DC. Mr. Bendis is reviewing panel submissions in the eHealth IT Track.

 

 

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ROCKVILLE, MARYLAND, February 11, 2013 – BioHealth Innovation, Inc. (BHI), a regional private-public partnership focusing on commercializing market-relevant biohealth innovations and increasing access to early-stage funding in Central Maryland, announced today the appointment of GenVec, Inc. President and Chief Executive Officer Cynthia L. Collins to its Board of Directors. BHI also announced that BHI Founding Board Member Jerry Parrott, formerly with Human Genome Sciences, has stepped down from his board seat but will continue to remain active on BHI's Commercial Relevance Advisory Board.

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ROCKVILLE, MARYLAND, February 27, 2013 – BioHealth Innovation, Inc. (BHI), a regional private-public partnership focusing on commercializing market-relevant biohealth innovations and increasing access to early-stage funding in Central Maryland, announced today the formation of its Commercial Relevance Advisory Board (CRAB). Members of the CRAB represent diverse business and academic organizations from throughout the region, such as venture capital firm New Enterprise Associates, Ernst & Young, the Howard Hughes Medical Institute, the University of Maryland (UMD), Johns Hopkins University, and leading biotechnology companies.

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BHI and Ahead are collaborating to accelerate commercialization of Symcat, Ahead Research’s patient/healthcare provider matchmaking app

ROCKVILLE, MARYLAND, Dec. 19, 2012 - BioHealth Innovation, Inc. (BHI) announced today that its newest client, Ahead Research, Inc. (Ahead), received the first Cigna Innovation Health Challenge award at the 2012 mHealth summit. BHI and Ahead recently signed a Memorandum of Understanding (MOU) to jointly accelerate the commercialization of Symcat, Ahead’s web and mobile application whose module was the basis for the Cigna award.

“Ahead Research – with its Symcat app – is the type of entrepreneurial start-up company that BioHealth Innovation seeks to foster as part of its mission to drive the commercialization of market-relevant biohealth innovations,” said BioHealth Innovation’s President & CEO Richard Bendis.

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ROCKVILLE, MARYLAND, Dec. 19, 2012 - BioHealth Innovation, Inc. (BHI), a regional private-public partnership focusing on commercializing market-relevant biohealth innovations and increasing access to early-stage funding in Central Maryland, announced today the appointment of Emergent BioSolutions Inc. President and CEO Daniel J. Abdun-Nabi and SR One President Jens Eckstein, Ph.D., to the BHI Board of Directors.

"It is an honor to welcome two additional life science industry leaders to the BHI Board of Directors," said BioHealth Innovation's President & CEO Richard Bendis. "Dan brings a unique perspective from his role at the helm of one of the leading specialty pharmaceutical companies while Jens will provide important insight as the head of the corporate venture capital arm of GlaxoSmithKline (GSK). I'm also incredibly pleased that GSK, after having acquired Human Genome Sciences (one of the original investors in BHI), will continue to support BHI and has expressed an understanding of the importance of the mission of our organization."

Maryland-based non-profit aims to cultivate regional biotechnology, medical device, and health care services companies

ROCKVILLE, MARYLAND, February 21, 2012 BioHealth Innovation, Inc. (BHI), a new regional private-public partnership focusing on commercializing market-relevant biohealth innovations and increasing access to early-stage funding in the Central Maryland, announced today the appointment of its Board of Directors, including Scott Carmer, MedImmune Executive Vice President of Commercial Operations, as Chairman. 

Partnership aims to accelerate technology transfer from federal labs to grow businesses and jobs 

ROCKVILLE, MARYLAND, March 12, 2012 BioHealth Innovation, Inc. (BHI), a new regional private-public partnership focusing on commercializing market-relevant biohealth innovations and increasing access to early-stage funding in Central Maryland, announced today it has entered into a Partnership Intermediary Agreement (PIA) with the National Institutes of Health’s (NIH) Office of Technology Transfer (OTT). As a partnership intermediary for NIH OTT, BHI will assist, counsel, advise, evaluate and cooperate with small businesses or educational institutions to make productive use of technologies from a federal laboratory.

Chappell will help start-ups based on innovative discoveries from NIH and FDA research programs 

ROCKVILLE, MARYLAND, March 26, 2012 BioHealth Innovation, Inc. (BHI), a new regional private-public partnership focusing on commercializing market-relevant biohealth innovations and increasing access to early-stage funding in Central Maryland, announced today its selection of Todd Chappell as the first Entrepreneur-in-Residence (EIR) for BHI at the National Institutes of Health (NIH) Office of Technology Transfer (OTT). Mr. Chappell, a venture capital-backed entrepreneurial leader and inventor with more than ten years of experience in molecular biology research, drug development and life sciences business strategy, will help support the development of new start-up companies based upon OTT technology license agreements.

- Seasoned executive adds depth in diagnostics and international experience to organization’s board – 

ROCKVILLE, MARYLAND, April 30, 2012 BioHealth Innovation, Inc. (BHI), a regional private-public partnership focusing on commercializing market-relevant biohealth innovations and increasing access to early-stage funding in Central Maryland, announced today the appointment of Douglas Liu, Senior Vice President of Global Operations at Qiagen, to its Board of Directors.

Distinguished entrepreneurial and innovation-based economic development leader to lead efforts of newly created innovation intermediary focused on accelerating biohealth commercialization for Central Maryland  

ROCKVILLE, MARYLAND, June 13, 2012 BioHealth Innovation, Inc. (BHI), a regional private-public partnership focusing on commercializing market-relevant biohealth innovations and increasing access to early-stage funding in Central Maryland, announced today that its Board of Directors has named former Interim CEO Richard Bendis as the organization's first President & Chief Executive Officer. 

ROCKVILLE, MARYLAND, July 23, 2012 BioHealth Innovation, Inc. (BHI), a regional private-public partnership focusing on commercializing market-relevant biohealth innovations and increasing access to early-stage funding in Central Maryland, announced today that it has located its corporate headquarters in the historic Wire Hardware Building at 22 Baltimore Road in Rockville. BHI also announced the creation of two new staff positions filled by recent hires Ethan Byler as Director of Innovation Programs and Amanda Wilson as Operations Manager.

- Event to Feature Company Presentations, Investor Panel Highlighting How to Turn Innovation into Commercialization - 

ROCKVILLE, MARYLAND, October 4, 2012 – BioHealth Innovation, Inc. (BHI), a regional private-public partnership focusing on commercializing market-relevant biohealth innovations and increasing access to early-stage funding in Central Maryland, announced today its role as a co-sponsor of the National Institutes of Health’s (NIH) National Heart, Lung, and Blood Institute’s (NHLBI) First Mid-Atlantic Innovation Conference. The Conference, which is designed to bring together small businesses, angel investors, venture capitalists, strategic partners, and business leaders from the biotech and pharmaceutical industries, will be held on Monday, October 15 from 8:30 a.m. until 1:00 p.m. at Johns Hopkins University, Montgomery County Campus, 9601 Medical Center Drive, Gilchrist Hall Auditorium, in Rockville, Maryland.

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Rockville, Maryland’s Fina Biosolutions recently was awarded an SBIR grant to develop a genetically detoxified tetanus toxin as a carrier protein for conjugate vaccines.  The NIAID funded grant is for $289,000 and will use a mutant toxin engineered by Dr. Joseph Barbieri of the Medical College of Wisconsin.  FinaBio’s Scientific Director, Andrew Lees, noted “We are very appreciative of the help from BHI in securing this grant which will help us to commercialize a new genetically detoxified vaccine carrier protein that complements our existing conjugate vaccine portfolio.” FinaBio has created an E. coli strain with an oxidative intracellular environment that grows to very high densities and can express soluble disulfide bonded proteins. The mutant tetanus toxin will be produced in this E. coli strain and compared as vaccine carrier protein with the chemically detoxified protein.  Fina Bio received assistance from This email address is being protected from spambots. You need JavaScript enabled to view it. in preparing the SBIR grant application through its Federal Funding Assistance program.

 
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Dear friends,


Last Friday, the emocha team onboarded two of our newest video DOT partners: San Diego County and the State of Delaware. From Collin County, TX, to Columbus, OH, we’ve continued working with innovative tuberculosis programs to make directly observed therapy more convenient and cost-effective.

We're taking all opportunities as we grow to gather user feedback and improve the emocha experience for patients and providers. That’s why earlier this month, our team visited the Puerto Rico Department of Health to learn how our technology has impacted their TB program.

In late 2016, the island was dealing with a TB outbreak in a facility for mentally impaired men. We volunteered the emocha platform pro bono to help manage the outbreak with Dr. Dana Thomas, then Medical Director, championing the effort on behalf of the TB program. Within months, all patients using emocha showed clinical signs of improvement.  

“emocha is so important because we have lost staff and fiscal resources over the years,” said Dr. Olga Joglar, TB Control Program Director.


In Puerto Rico and around the country, emocha helps public health departments save time and money on DOT programs. NIH-supported research shows that our platform for video observation can secure 92% adherence with significant cost savings.
 

READ MORE FROM THE NIH

The emocha platform is used worldwide for TB, HCV, HIV and opioid use disorder treatment. Ready to learn more? Visit our website or reach out at This email address is being protected from spambots. You need JavaScript enabled to view it.

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Sonavex, a Baltimore-based medical device company, has announced a raise of $3M in financing including the first close of its Series A round led by Grey Sky Partners. Recently named Maryland’s 2016 Incubator Company of the Year, Sonavex is focused on improving surgical patient outcomes with point-of-care imaging technologies. Other organizations participating in this financing include CRCM Venture Capital, TEDCO, and the Abell Foundation. Award of a $750k Phase II SBIR grant from the National Science Foundation is also included in the financing. With this influx of capital, Sonavex will be advancing the commercialization of EchoSure, a Doppler ultrasound system, and developing additional ultrasound solutions currently in the company’s pipeline. The press release also announces the addition of Bill Niland, CEO of Harpoon Medical, and Bob Hallenbeck, former executive at Becton Dickinson, to Sonavex’s Board of Directors.

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Sisu Global Health got more recognition for its device that recycles blood for use during surgery, winning the First Mile Innovation Challenge.

The competition, which was run by the Consortium of Affordable Medical Technologies (CAMTech), GE Sustainable Healthcare Solutions and MGH Global Health, sought applications from around the world that address health hardships in low and middle income countries. About 80 companies from 16 countries applied, according to an announcement.

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Redox, a Madison, WI-based startup that develops digital tools that enable healthcare applications to access data from electronic health records systems, says it has raised $9 million from investors.

New York-based RRE Ventures led the Series B financing. Other participants in the funding round included return backers .406 Ventures (in Boston), HealthX Ventures (Madison), and Flybridge Capital Partners, which has offices in Boston and New York. .406 Ventures led Redox’s $3.5 million Series A round, which was announced in late 2015.

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Since its inception, biotechnology has been preoccupied with virus filtration, the clearance of invasive and adventitious viruses from biopharmaceutical products. And now, far from waning, virus filtration is set to become even more important. Virus filtration, reports Markets and Markets, constitutes a global market that is growing 12% each

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The NIH has awarded MIMETAS and the University of Pittsburgh a prestigious SBIR grant to develop a Liver-on-a-Chip platform for high throughput discovery and development. Accurate prediction of hepatotoxicity is a major problem in the development of new drugs leading to high development costs.  Animal hepatotoxicity testing is expensive, unsuited to high throughput and overall has unreliable concordance with human hepatotoxicity. MIMETAS scientists have teamed up with the University of Pittsburgh Drug Discovery Institute led by D. Lansing Taylor, Ph.D. to develop a liver-on-a-chip platform of unprecedented throughput, predictivity and usability. “We’re extremely happy to be working with Lans and his team on this project”, says Dr. Anthony Saleh of MIMETAS. “Prof. Taylor is a frontrunner in developing in vitro liver cultures and has vast experience with microfluidic techniques." “We were extremely impressed when we learned about the MIMETAS OrganoPlate platform”, commented Prof. Taylor. “It enables High Throughput, 3D co-culture with a vascular and hepatic compartments, as well as ease of handling. There is really no equivalent in the Organ-on-a-Chip space”.

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Great news in the happiest season of the year. We've published our 3D neuronal models for drug screening in Nature Scientific Reports and we received a grant with Pittsburg University for liver-on-a-chip. Of course we're looking forward to meet you at the SLAS2017 in Washington and at the ISSCR in Basel. And Christmas would not be Christmas without our warm wishes for the holiday season and the year 2017. We're definitely looking forward to it!

Every year, millions of fish raised in aquaculture die of nervous necrosis virus (NNV). “The disease affects the brain, and the fish lose their vision and balance,” says Vikram Vakharia, professor of marine biotechnology at UMBC. As a result of damage to the nervous system, “the fish just swim in circles,” Vakharia says. His lab is housed at the Institute of Marine and Environmental Technology (IMET) on Baltimore’s Inner Harbor.

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Leiden-based biotechnology company Mimetas has received 1.6 million USD funding for development of an organ-on-a-chip model for neurotoxicity. The aim of the project is to improve existing neurotoxicity tests and to reduce experimentation on animals. A panel of experts from BASF, Sanofi, GlaxoSmithKline, Abbvie, NC3Rs and renowned academic institutions has selected the Mimetas solution from a lineup of strong competitors. Mimetas will lead the consortium, which also includes the Institute for Risk Assessment Sciences (Utrecht, The Netherlands) and Cellular Dynamics International (Wisconsin, USA).

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Rockville, MD, November 19, 2014 – BeneVir BioPharm, Inc. today announced it closed a Series A investment round with Pansend, LLC, an indirect wholly owned subsidiary of HC2 Holdings, Inc. (OTCQB: HCHC). BeneVir’s core technology was licensed from New York University (NYU) and originally developed by Ian J. Mohr, Ph.D., NYU Langone Medical Center.

BeneVir used this core technology to develop a pipeline of cancer immunotherapy drug candidates that affect antigen presentation in both tumor cells and antigen presenting cells. BeneVir’s pipeline consists of oncolytic viruses delivered locally or systemically. Once inside tumors, the viruses selectively destroy cancer cells, evade elimination by the immune system, and activate multiple classes of anti-tumor immune cells. This multi-mechanistic approach builds upon key elements of both oncolytic virus and immune-checkpoint inhibitor approaches to cancer treatment and is designed to block the major methods that tumors use to subvert the immune system. Proceeds of the financing will be used to conduct initial proof- of-concept clinical studies of BeneVir’s lead product, further develop the pipeline, and establish partnerships to test promising combination therapies in a diverse set of metastatic solid tumors.

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Benevir has been accepted into the Hive program and will be taking part in the TEDMED 2014 convention from September 10-12, 2014 in Washington, DC and San Francisco.

BeneVir's cancer therapeutic is designed to induce the immune system to recognize and rid the body of two types of tumor cell. The first type is responsive to current immunotherapies, and many patients experience complete remissions. Tumor cells of the second type have evolved to hide from the immune system and are refractory to current immunotherapies. These tumor cells are ultimately responsible for tumor recurrence and poor clinical outcomes. To our knowledge, there is no technology in development that can induce immunity to both types of tumor cell. We feel we have a unique perspective in the emerging field of cancer immunotherapy and that our technology will exhibit enhanced clinical benefit for a wide range of cancer patients.

Read the full interview after the jump!

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We are pleased to announce that emocha Mobile Health launched its video-based directly observed therapy application, miDOT, in Harris County, Texas. miDOT will be used to bridge the distance between healthcare workers and the tuberculosis (TB) patients that are dispersed across the nearly 1,800 square miles surrounding Houston, which has one of the nation’s highest Tuberculosis rates. The roll-out began in early February after emocha won a competitive bidding process based on a head-to-head pilot with competing technologies.

July 8 - 9, 2015, Boston, MA, USA

The first ever Organ-on-a-Chip World Congress focuses on Organ-on-a-Chip technology, Biofabrication and 3D-Bioprinting in the life sciences. The conference will be held on 8-9 July 2015 in Boston, organized by Selectbio.

MIMETAS is corporate sponsor of this inaugural conference.

Oral Presentation Abstract Submission Deadline: February 27, 2015

Poster Submission Deadline: June 30, 2015

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Maarssen, the Netherlands, 14 June 2013 - MIMETAS was awarded the prestigious LifeSciences@Work award during yesterdays' Dutch Life Sciences SME Event. 75 recently established Life Science companies were invited to compete through an on-line video pitch contest. The video pitches were analyzed by a professional jury, consisting of primarily investors and life science professionals.

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MIMETAS today announces the appointment of Herbert L. Heyneker, Ph.D. as Chairman of the Board of Directors. Dr. Heyneker will be supporting MIMETAS in her mission to develop high-throughput Organ-on-a-Chip products for predictive therapy testing.

"Organ-on-a-Chip technology is extremely hot in the United States today. But none of the technologies I've seen so far comes even close to the level of elegance and sophistication that MIMETAS is offering." says Herb Heyneker, who is based in the San Francisco Bay area. "I am strongly convinced that MIMETAS technology has the potential to create a revolution in medicine development and therapy selection. [...]"

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MIMETAS' co-founder Paul Vulto has won the Audience Award and the runner up Jury Award for Best Proposition at the International Conference on the Commercialisation of Micro- and Nanosystems (COMS). The jury, which included serial entrepreneur Steven Walsh and Silicon Valley entrepreneur Janusz Bryzek, called the MIMETAS proposition a technology that will change the world, having the potential to grow into a billion-dollar company.

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The UK-based National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs) has awarded MIMETAS with £100k in the NephroTube Crack-it Challenge, sponsored by GlaxoSmithKline, Pfizer and Roche.

The NephroTube Crack-it Challenge aims to develop a microfluidic renal model predicting renal toxicity during pre-clinical development. In collaboration with the UMCN Pharmacology-Toxicology Department and the Swiss FHNW, MIMETAS will develop a kidney-on-a-chip by combining its OrganoPlate™ 3D-culturing technology with the human renal cell line ciPTEC™.

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