New Device Provides an Effective, Hands-Free Solution to Stop Nosebleeds in Children and Adults

Adult and Pediatric NasaClip Sizes Provide Easy-To-Use Options for Chronic Nosebleed Sufferers, Healthcare Professionals, Parents, and Schools; First Available, U.S. Food and Drug Administration Registered Device with Age-Appropriate Sizing for Patients Aged 2 and Older

BALTIMORE, MD. (PRWEB) JULY 11, 2023

NasaClip, Inc., a Baltimore-based medical device company focused on improving the lives of patients with nosebleeds and the healthcare professionals who treat them today introduced the NasaClip, an easy-to-use device that provides constant, comfortable hands-free compression combined with intranasal sponges to stop nosebleeds quickly. NasaClip comes in an adult size for ages 14+, and pediatric size for children ages 2 to 13. It is the first nosebleed rescue device that provides adjustable nasal compression for children and adults and is registered with the U.S. Food and Drug Administration (FDA).

Baltimore-based Digital Health Startup is Working to End Medication Errors and Streamline Workflows in Long-Term Care Settings

Baltimore, Md. (July 11, 2023) – Impruvon Health (“Impruvon”), a Baltimore-based digital health startup, announced today that it closed a financing round to support surging demand from healthcare organizations for its enterprise medication management platform. The round is led by The Propel Baltimore Fund from TCP Venture Capital, with participation from the University System of Maryland (USM) Momentum Fund (Momentum Fund) and New Dominion Angels.

Responding faster and more effectively to future public health challenges and emergencies will require the development of a specific, rapid acquisition vehicle. To achieve this, BARDA is launching the Rapid Response Partnership Vehicle (RRPV), the next generation of acquisition partnering to support U.S. health security.

In alignment with objectives outlined in the 2022-2026 Strategic Plan, BARDA seeks to leverage its Other Transaction Authority (OTA) to develop the RRPV. The RRPV will complement BARDA’s existing acquisition vehicles such as the Broad Agency Announcement (BAA) and the Easy Broad Agency Announcement (EZ-BAA) and will expand the mechanisms through which BARDA can rapidly partner with product developers prior to and during an emergency response. With the RRPV in place, BARDA will be able to leverage OTA agreements to meet the dynamic needs of the BARDA mission through a streamlined, expedited process.

The long-awaited grand opening of the Sfax University Simulation Center has finally arrived, marking a new era of innovative learning and development in Sfax, Tunisia. The cutting-edge center promises to provide a hub for experiential learning, creating a springboard for high-potential projects to flourish. In the run-up to the opening, the team at the Simulation Center, supported by Johns Hopkins University,  held a series of fruitful meetings with local stakeholders. During these sessions updates were shared, and attendees were encouraged to submit their high potential projects for consideration, initiating direct engagement with the local community.

MaxCyte’s Flow Electroporation® technology and ExPERT™ platform will support Vittoria’s Senza5™ technology to enhance efficacy and improve clinical utility of T-cell therapies.

ROCKVILLE, Md. and PHILADELPHIA, July 10, 2023 (GLOBE NEWSWIRE) -- MaxCyte, Inc., (Nasdaq: MXCT; LSE: MXCT), a leading, cell-engineering focused company providing enabling platform technologies to advance the discovery, development and commercialization of next-generation cell-based therapeutics and to support innovative, cell-based research, and Vittoria Biotherapeutics (Vittoria), a leading edge, gene-edited cell therapeutics company with novel platform technologies poised to develop a pipeline of highly differentiated cellular therapies for both oncology and immunology indications, today announced the signing of a strategic platform license (SPL) of MaxCyte’s Flow Electroporation® technology and ExPERT™ platform to Vittoria Biotherapeutics.

Ever wondered how public-private partnerships can make a significant difference in the field of life sciences? Curious about the goals, expected impacts, and timeline of the Alliance for Building Better Medicine (ABBM)? Interested in exploring the transformative potential of the Virginia BioHealth ecosystem and its role in advancing the life sciences industry?

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FREDERICK, MARYLAND, July10, 2021: BioFactura, Inc. today announced that CuraTeQ Biologics Private Limited, a wholly owned subsidiary of Aurobindo Pharma Limited, has entered into an exclusive license to commercialize BFI-751, BioFactura’s proposed biosimilar to Stelara (Ustekinumab). Ustekinumab is a recombinant monoclonal antibody that works by blocking both interleukins IL-12 and IL-23 and is used for treating Crohn's disease, ulcerative colitis, plaque psoriasis and psoriatic arthritis. The global drug sales of Ustekinumab stood at close to 10 billion in 2022 presenting a significant opportunity with a good number of indications and a wider use.

WASHINGTON–(BUSINESS WIRE)–Parker Health an innovative biotech company for electronic health records, hospital developer & management, and subscription-based health services, today announced that it has secured $25 million in Series A funding led by Bias Capital a multisector and multi-stage angel syndicate joined in this round by L’PAJ Ventures, CGT Capital Group, and other angel investors and family offices. This funding empowers Parker Health to further its position as the industry’s most compliant and competitive solution helping expand our medical technology and services and to employ global teams. Parker Health has raised $26.3 million to date.

The National Institutes for Health (NIH) has awarded $4.4 million to a University of Maryland researcher and a colleague to develop both a novel therapeutic and a vaccine approach to address Streptococcus pneumoniae, which is the leading cause of bacterial community-acquired pneumonia and the cause of death for about 1.6 million people annually.

Pneumococcal vaccinations are very effective, but target just a few of the more than 100 different strains of pneumococcus; they’re also unavailable in many developing countries. Additionally, antimicrobial resistance is on the rise globally, and poses a risk of pneumococcal disease that is increasingly difficult to combat.

Expectations are high for combining human and artificial intelligence against health problems.

“Start by determining the problem you desire to solve, then decide on the technology to solve it,” said Subha Madhavan, vice president and head of clinical artificial intelligence/machine learning with global biopharmaceutical company Pfizer. 

Madhavan was the keynote speaker at AI for Pediatric Health and Rare Diseases, an inter-institutional meeting of scientists and innovators co-led by Children’s National Hospital and the Virginia Tech Sanghani Center for Artificial Intelligence and Data Analytics to discuss the potential of artificial intelligence (AI) to understand pediatric health.

FREDERICK, Md., July 6, 2023 /PRNewswire/ -- Today, Theradaptive, a biopharmaceutical firm pioneering advancements in targeted regenerative therapeutics, has been awarded the Manufacturing Assistance Program grant by the Maryland Stem Cell Research Fund (MSCRF). The grant will help Theradaptive develop their GMP Manufacturing Facility in Frederick, stimulating economic development in the state and bolstering Maryland's reputation as a hub of biotechnological innovation.

Theradaptive seeks to significantly improve patient outcomes by producing targeted therapeutics that can be used to coat implants, devices, and injectable carriers. Their proprietary protein-engineering platform aims to provide greater efficacy, safety, and ease of use across multiple clinical indications including orthopedics, immuno-oncology and dental.

Lyell Immunopharma to use MaxCyte’s Flow Electroporation® technology and ExPERT™ platform in its T cell product candidates targeting solid tumors.

ROCKVILLE, Md., July 06, 2023 (GLOBE NEWSWIRE) -- MaxCyte, Inc., (Nasdaq: MXCT; LSE: MXCT), a leading, cell-engineering focused company providing enabling platform technologies to advance the discovery, development and commercialization of next-generation cell-based therapeutics and to support innovative, cell-based research, today announced the signing of a strategic platform license (SPL) with Lyell Immunopharma, Inc., a clinical stage T cell reprogramming company.

George Mason University/USDA team find probiotics counter high fat diets in pigs

FAIRFAX, Virginia - According to a new study published by George Mason University researchers Dr. Robin Couch and Dr. Allyson Dailey, in collaboration with researchers at the U.S. Department of Agriculture (USDA), showed probiotics may play a pivotal role in preventive medicine.

High fat diets are a leading cause of obesity and can trigger the onset of metabolic syndrome. The research team found that probiotic intervention has significant potential for addressing obesity-related diseases.

Join us on a compelling episode of BioTalk as we sit down with three dynamic leaders from groundbreaking MedTech companies based in the thriving BioHealth Capital Region. These companies, JuneBrain, Xcision Medical Systems, and Sonavi Labs, were recently selected for the prestigious MedTech Innovator Accelerator, the world's largest accelerator of medical technology companies. Discover their innovative solutions and the transformative impact they are making in healthcare.

Galen Robotics, Inc. was the winner of the 2018 BioHealth Capital Region Crab Trap Competition

COLUMBIA, Md. (June 27, 2023) – TEDCO, Maryland’s economic engine for technology companies, announced a recent $500,000 Seed Funds investment into Galen Robotics, Inc. This round of seed funding is from the Life Sciences Investment Fund.

Bruce Lichorowic, Galen Robotics CEO“In 2017, Galen successfully secured our first MII Phase III grant which led us to make the decision to relocate our headquarters from Silicon Valley to Baltimore. Now, as we receive a follow-up investment, it is evident that TEDCO remains committed to supporting and nurturing its portfolio companies. Despite the macroeconomic challenges associated with early-stage funding, TEDCO has established itself as a leader in investing in high-quality startups based in Maryland. Their dedication to supporting local entrepreneurship is commendable and sets them apart in the startup ecosystem,” said Bruce Lichorowic, president and CEO of Galen Robotics. “TEDCO serves as a valuable resource for Maryland's early-stage technology companies, offering not only funding opportunities but also mentorship, marketing strategies and introductions to key leaders within the government and industry. With these comprehensive support services, TEDCO becomes an indispensable resource that empowers startups to progress and reach the next level of their development.”

GAITHERSBURG, Md., June 27, 2023 (GLOBE NEWSWIRE) -- Emergent BioSolutions (NYSE: EBS, “Emergent” or the “Company”) today announced that Robert G. Kramer Sr. has informed the Board of Directors of his intention to retire from Emergent. Mr. Kramer will step down from his role as President and CEO of Emergent and as a member of the Company’s Board, effective immediately. The Board has appointed Haywood Miller as interim CEO while it conducts a search to identify a new permanent CEO, considering both internal and external candidates and with the assistance of a leading executive search firm. Mr. Miller, Managing Director at Berkeley Research Group (“BRG”), has served as an advisor to the Company and its executive management team for the last several months. In order to ensure a smooth transition, Mr. Kramer will serve as an advisor to the Company until August 1, 2023.

As Dr. Kurt Newman, President and CEO of Children’s National Hospital, prepares for retirement, BioHealth Innovation, Inc. (BHI) honors his exceptional contributions and visionary leadership in pediatric health and the BioHealth Capital Region. Since assuming the role of CEO in 2011, Dr. Newman has championed patient-centered care and driven innovation in research, operations, and clinical practices at Children’s National Hospital.

Under his guidance, Children’s National has formed successful partnerships with health systems, government entities, and community organizations, boosting pediatric healthcare forward and benefiting countless children and families. Dr. Newman’s advocacy for expanding mental health access for kids has significantly impacted many. He has led national forums on this critical issue, raising awareness and integrating mental health support within pediatric care.

Maryland company focused on innovating solutions for complex brain surgeries

COLUMBIA, Md. (June 26, 2023) – Jesse Christopher, Longeviti co-founder and CEOTEDCO, Maryland’s economic engine for technology companies, announced a $500,000 State Small Business Credit Initiative (SSBCI) investment into Longeviti Neuro Solutions, LLC (Longeviti). This SSBCI investment came out of TEDCO’s Venture Funds.

“We saw an opportunity to improve the lives of patients undergoing complex surgeries, and we’re glad we took it,” said Jesse Christopher, Longeviti co-founder and CEO. “Thanks to TEDCO’s investment, we can continue innovating, working towards solutions and helping patients.”

Are you curious to discover how experts navigate the complex landscape of life sciences real estate? Want to stay ahead of the curve in the market today? Ready to learn about the latest talent dynamics in the field?

Join Rich Bendis on BioTalk as he discusses the world of life sciences real estate and market trends with CBRE’s experts, Dan Grimes, Senior VP at CBRE’s Mid-Atlantic Life Sciences practice, and Ian Anderson, Senior Director of Research and Analysis. Together, they discuss the 2023 “US Life Sciences Research Talent Report” and the BioHealth Capital Region’s Top 3 ranking.

Discover how Dan’s expertise in real estate strategies for BioHealth companies and investors shapes success in the industry. Gain valuable insights from Ian’s extensive experience in commercial real estate and capital markets as he guides decision-making in the life sciences, office, and healthcare sectors. They discuss major BioHealth projects, delve into talent dynamics, and analyze market trends.

Modifying patients’ T-cells with mRNA to express a chimeric antigen receptor (rCAR-T therapy), a novel approach to treat myasthenia gravis and other autoimmune diseases.

Gaithersburg, MD—June 22, 2023 – Cartesian Therapeutics, a clinical-stage biotechnology company pioneering cell therapies for autoimmune diseases, announced today the publication of a landmark paper in The Lancet Neurology. The study describes Descartes-08, a cutting-edge RNA CAR-T (rCAR-T) therapy administered to patients with generalized myasthenia gravis (MG), a debilitating autoimmune neurological disease. The data demonstrate marked and long-lasting clinical improvement in patients with MG. This is the first clinical trial using rCAR-T to treat autoimmunity, and the first successful Phase 2 trial using an engineered cell therapy to treat autoimmunity.

Maryland life sciences company fighting antibiotic resistance, one innovative tech at a time

COLUMBIA, Md. (June 22, 2023) – TEDCO, Maryland’s economic engine for technology companies, announced a Seed Funds investment of $250,000 into Astek Diagnostics, a life sciences company fighting antibiotic resistance through innovative technology. In addition to this investment through the Life Sciences Investment Fund – a funding opportunity under the umbrella of TEDCO’s Seed Funds – Astek Diagnostics has received an additional $325,000 from the State Small Business Credit Initiative (SSBCI) funding.

The transformational investment is one of the hospital’s largest donations ever. It will power discoveries and revolutionize care for children and families who receive a brain tumor diagnosis.

June 21, 2023 - Children’s National Hospital announced a $96 million investment from an anonymous donor family that strengthens its globally recognized leadership to transform rare childhood brain tumor research and care. It is one of the largest donations in the hospital’s history. It allows Children’s National to recruit more top talent and advance the most promising research for safer, more effective treatments. The investment will elevate standards of care to help children with rare brain tumors thrive for a lifetime.

ANNAPOLIS, MARYLAND, UNITED STATES, June 20, 2023/EINPresswire.com/ -- The study, “Advanced Prediction of Respiratory Depression Episodes with Linshom Continuous Predictive Respiratory Monitoring (CPRM)” began patient enrollment in March, 2023 and has enrolled over 90 patients; more than half of the enrollment target for phase one of the study.

“This study intends to prove Linshom Medical’s ability for early detection of patient respiratory decline”, said Richard Hughen, CEO. “Current standard of care and technology provide warnings after the patient is in trouble. If we get in front of this with predictive capability, we should be able to avoid costly rapid response activation, rescue events and ICU transfers”.

Sykesville, Maryland – June 20, 2023
Noble Life Sciences, a leading contract research organization in Maryland, is proud to announce that it has received renewed accreditation from the Association for Assessment and Accreditation of Laboratory Animal Care (AAALAC) International. This recognition validates Noble’s responsible treatment of animals in its research, solidifying it as a top-tier organization serving the biotechnology, biopharmaceutical, and pharmaceutical industries.

As the AAALAC is the foremost authority in accrediting animal care and use programs for research, testing, and teaching worldwide, accreditation from AAALAC International is a significant achievement. With its rigorous evaluation process and commitment to ensuring ethical treatment of animals, AAALAC has become the trusted accreditation agency for professionals across the globe.

GERMANTOWN, Md. , June 20, 2023 /PRNewswire/ -- Precigen, Inc. (Nasdaq: PGEN), a biopharmaceutical company specializing in the development of innovative gene and cell therapies to improve the lives of patients, today announced that the US Food and Drug Administration (FDA) has granted Breakthrough Therapy Designation for the first-in-class investigational PRGN-2012 AdenoVerse immunotherapy for the treatment of recurrent respiratory papillomatosis (RRP).

FDA's Breakthrough Therapy Designation expedites the development and review of medicines which are intended to treat serious or life-threatening diseases, and in which preliminary clinical evidence demonstrates substantial improvement on clinically significant endpoints over available therapies.

— New Financing of $24 Million Fully Funds the Phase 2 Clinical Program for Lead Candidate VLX- 1005

— Company Prepares to Evaluate VLX-1005 in Heparin-Induced Thrombocytopenia (HIT)

FREDERICK, Md., June 20, 2023 (GLOBE NEWSWIRE) — Veralox Therapeutics, a clinical-stage biotechnology company developing a new class of therapies targeting the 12-lipoxygenase (12-LOX) pathway to address some of medicine’s most persistent and serious immune-mediated diseases, today announced the appointment of Jonathan Mow as the company’s new chief executive officer.

Mr. Mow’s appointment comes as Veralox secured $24 million in funding to advance VLX-1005 through a Phase 2a proof-of-concept study evaluating its impact on heparin-induced thromobcytopenia (HIT), a life-threatening rare disease caused by an aberrant immune response to heparin exposure. The investment round included new investors Pappas Capital and NYBC Ventures and existing investors Hatteras Venture Partners, Sanofi Ventures, JDRF T1D Fund and Genesys Capital, amongst others. In conjunction with the financing, the company welcomes Peter Young of Pappas Capital as a director and Meg Wood of NYBC Ventures as an observer.

BioHealth Innovation, Inc. (BHI), in collaboration with the Global Business Center (GBC) – Washington, D.C. of Korea SMEs and Startups Agency (KOSME), is excited to announce the continuation of their highly successful program aimed at facilitating Korean companies' entry into the US market. As the program enters its third year, it continues to empower Korean biotech enterprises, enabling them to establish a strong foothold in the BioHealth Capital Region. KOSME is a Korean-government funded non-profit, currently led by President, Dr. Hakdo Kim, created over forty years ago to support small and medium enterprises in Korea.

"We are thrilled to continue our partnership with BHI for the third year in a row. The program has consistently provided guidance and market knowledge, proving invaluable to Korean biotech companies. We anticipate that our latest cohort will benefit greatly from this collaboration," says Rich Bendis, President and CEO of BHI.

BioHealth Innovations (BHI) is thrilled to welcome Ashleigh Acker and Sebastian Chung as the newest additions to our internship program. Their diverse backgrounds and passion for biotechnology make them valuable assets to our organization.

Sebastian Chung, a graduate student at Johns Hopkins University, is on track to complete his Master's in Biotechnology in the spring of 2024. During his undergraduate years at the University of Washington in Seattle, Sebastian excelled in the study of physiology and sales, all while co-captaining the men's club golf team. His expertise lies within the multi-omic space, having worked as an account manager at NanoString Technologies, a leading biotechnology company. Sebastian's extensive experience in consulting on sequencing and spatial biology projects, particularly with large pharmaceutical companies in the greater New England area, will undoubtedly contribute to our innovative research initiatives. When he's not immersed in the world of biotechnology, Sebastian enjoys playing golf and watching premier league soccer.

In this captivating episode of BioTalk, Rich Bendis sits down with Tom Sadowski, the Executive Director of the Maryland Economic Development Corporation (MEDCO). With over 30 years of experience in economic development, Tom has played a pivotal role in translating vision into action. Together we explore MEDCO’s significant contributions to economic development and their strategic partnerships across Maryland.

Tom shares his remarkable career accomplishments, including successful projects valued at over $10 billion and the creation of 50,000 jobs. His expertise in fostering research partnerships, technology commercialization, and his role in launching the Maryland Momentum Fund bring invaluable insights to the conversation. We uncover MEDCO’s focus on real estate development, financing, infrastructure, and public/private partnerships, all aimed at fueling business retention, development, and employment growth.

The long-anticipated intramural licensing impact study was officially released in conjunction with the BIO Annual Meeting and is now posted to a special section of the NIH Community Tech Transfer Website for further reading and utilization.

The year-long study involved a full download and analysis of NIH TechTracs licensing data and demonstrates the true impact and power that our NIH intramural licensing program has had in three major areas:

AlphaTech, an esteemed initiative focused on fostering innovation within the cybersecurity, big data, analytics, and digital health sectors, is thrilled to announce the induction of a new cohort consisting of exceptional companies. The program, designed to engage with Founders and CEOs of emerging growth companies, aims to provide valuable resources, educational programming, networking opportunities, and meaningful interactions.

Over the course of eight months, this select group of CEOs will have the privilege of connecting with AlphaTech's advisors, speakers, alumni, and industry luminaries. The program's comprehensive approach encourages collaboration and knowledge sharing, ensuring participants gain insights from experienced professionals and industry veterans.

Neuroene Therapeutics has been awarded a Small Business Innovation Research (SBIR) grant by the National Institutes of Health (NIH). The award supports Neuroene’s ongoing research and development of a novel class of well-tolerated compounds protects and ameliorates mitochondrial and neurological diseases.

Neuroene’s lead antiseizure drug (ASD) candidate has demonstrated broad-spectrum antiseizure activity in several animal models of pharmacoresistant seizures and Parkinson’s disease, showcasing its potential both as a fast-acting rescue agent and long-term chronic therapeutic. Intriguingly, the compound’s stability offers significant advantages for long-term storage and stockpiling in case of public health emergencies or bio-incidents.

Frederick-based biopharmaceutical company Theradaptive Thursday announced it has closed a $26 million Series A funding round to advance development of its targeted regenerative therapeutics.

The funds are intended to enable the company to continue its work to meet regulatory requirements and scale up Good Manufacturing Practices in preparation for first-in-human clinical trials later this year. Investment will also support the expansion of the Theradaptive platform beyond orthopedics to additional indications such as oncology and dental. The round brings Theradaptive’s total funding to more than $50 million.

The company has previously been awarded non-dilutive grant funding from the Department of Defense, as well as the Maryland Stem Cell Research Fund.

Click here to read more via The Daily Record.

Countless medicines of tomorrow are being developed right here today — many in Montgomery County, among the country’s top life sciences hubs.

Here’s a look at three potential medical breakthroughs now in development at some of the region’s bioscience firms, how they got there and what to expect next.

Local life sciences, at a glance

Greater Washington and Baltimore combined to be the fifth-largest life science employment cluster in the United States, with roughly 75,000 in the workforce as of the second quarter of 2022, according to an April 2023 CBRE research report. The regions above it: San Francisco Bay Area, Boston/Cambridge, New Jersey and San Diego.